In recent years, significant progress has been made in building new galaxy clusters samples, at low and high redshifts, from wide-area surveys, particularly exploiting the Sunyaev-Zel'dovich (SZ) effect. A large effort is underway to identify and characterize these new systems with optical/NIR and X-ray facilities, thus opening new avenues to constraint cosmological models using structure growth and geometrical tests. A census of galaxy clusters sets constraints on reionization mechanisms and epochs, which need to be reconciled with recent limits on the reionization optical depth from cosmic microwave background (CMB) experiments. Future advances in SZ effect measurements will include the possibility to (unambiguously) measure directly the kinematic SZ effect, to build an even larger catalogue of galaxy clusters able to study the high redshift universe, and to make (spatially-)resolved galaxy cluster maps with even spectral capability to (spectrally-)resolve the relativistic corrections of the SZ effect.