Low Risk of Hypertrophic Cardiomyopathy With Contemporary Management Strategies Implemented in Non-Referral Regional Community-Based Practices

Shirani, Jamshid; Aurshiya, Rasha; Elshaikh, Abdelsalam; Olenchock, Stephen A.; Rowin, Ethan J.; Maron, Martin S.; Maron, Barry J.

doi:10.1016/j.amjcard.2020.11.035

Cited by 4 publications

(2 citation statements)

References 18 publications

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“…Nevertheless, unmet needs and challenges remain, including more widespread acceptance and implementation of these established treatment advances outside of dedicated HCM centers, including regional and community-based populations (74) and countries outside the United States with great numbers of HCM patients (e.g., China and India), often encumbered by societal, cultural, and resource obstacles (75). Also related to these objectives are efforts to resolve inequities in clinical care based on gender and race (17,18,76).…”

Section: Discussionmentioning

confidence: 99%

Hypertrophic Cardiomyopathy: New Concepts and Therapies

2022

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Hypertrophic cardiomyopathy (HCM), a relatively common, globally distributed, and often inherited myocardial disorder, transformed over the last several years into a treatable condition with the emergence of effective management options that alter natural history at all ages. Now available are a matured risk stratification algorithm selecting patients for prophylactic implantable defibrillators that prevent arrhythmic sudden death; low-risk, high-benefit surgical myectomy to reverse progressive heart failure symptoms due to left ventricular outflow obstruction; anticoagulation prophylaxis to prevent atrial fibrillation–mediated embolic stroke; and heart transplant for refractory end-stage disease in the absence of obstruction. Those strategies have resulted in reduction of HCM-related morbidity and reduction of mortality to 0.5% per year.

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Section: Discussionmentioning

confidence: 99%

Hypertrophic Cardiomyopathy: New Concepts and Therapies

2022

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“…20 In conclusion, HCM Summit conferences, in conjunction with an expansive body of knowledge, consensus state-ofthe-art expert panels, national societal guidelines, and regional meetings, represent important vehicles for disseminating data and information and encourage the exchange of ideas concerning the clinical and genetic complexity of HCM. The future challenges are those directed toward implementing innovative contemporary diagnostic and management strategies capable of reducing mortality and morbidity into regional practices 21 beyond major centers dedicated to the disease and bring the benefits of HCM treatments to affected patients in greatly populated but less industrialized parts of the world. 18,22…”

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confidence: 99%