Seismicity in both compressional and extensional settings is a function of local and regional stresses, rheological contrasts, and the distribution of fluids. The influence of these factors can be illustrated through their effects on electrical geophysical structure, since this structure reflects fluid composition, porosity, interconnection and pathways. In the compressional, amagmatic New Zealand South Island, magnetotelluric (MT) data imply a concave-upward ("U"-shaped), middle to lower crustal conductive zone beneath the west-central portion of the island due to fluids generated from prograde metamorphism within a thickening crust. Change of the conductor to near-vertical orientation at middle-upper crustal depths is interpreted to occur as fluids cross the brittle-ductile transition during uplift, and approach the surface through induced hydrofractures. The central South Island is relatively weak in seismicity compared to its more subduction-related northern and southern ends, and the production of deep crustal fluids through metamorphism may promote slip before high stresses are built up. The deep crustal conductivity is highly anisotropic, with the greater conductivity along strike, consistent with fault zone models of long-range interconnection versus degree of deformation. The central Great Basin province of the western U.S. by contrast is extensional at present although it has experienced diverse tectonic events throughout the Paleozoic. MT profiling throughout the province reveals a quasi one-dimensional conductor spanning the lower half of the crust which is interpreted to reflect high temperature fluids and perhaps melting caused ultimately by exsolution from crystallizing underplated basalts. The brittle, upper half of the crust is generally resistive, but also characterized by numerous steep, narrow conductors extending from near-surface to the middle crust where they contact the deep crustal conductive layer. These are suggested to represent fluidised/altered fault zones, with at least some fluids contributed from the deeper magmatic exsolution. The best-known faults imaged geophysically before this have been the listric normal faults bounding graben sediments as imaged by reflection seismology. However, the major damaging earthquakes of the Great Basin appear to nucleate near mid-crustal depths on near-vertical fault planes, which we suggest are being imaged with the MT transect data, and where triggering fluids from the ductile lower crust are available. In both compressional and extensional examples, the fluidised fault zones are hypothesized to act to concentrate slip, with major earthquakes resulting in asperities along the fault surface.