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Materials that have been engineered to interact with biological systems for medical purposes are biomaterials. There are natural and synthetic biomaterials designed for biomedical applications such as supporting tissue regeneration, replacing or repairing damaged organs or tissues, delivering drugs or therapeutic agents to specific sites, supporting medical devices and implantations including orthopaedic implants, cardiovascular stents, dental implants, wound dressing, etc. Surface coatings are often used on biomaterials to enhance their biocompatibility, durability, functionality, and corrosion resistance in biomedical applications. These coatings can modify the surface properties of biomaterials to better suit their intended use and improve their interaction with biological systems. The implanting material must not cause any toxic, allergic or inflammatory reactions in the cells of the body. The degradability of the material should be neither too long nor too short; it should fulfill its purpose and then leave the body. To improve such features for a coating, materials with different advantages are integrated to create functionalised bilayer and multiple-layer coatings. The widely used materials in coatings are ceramic materials like hydroxyapatite, natural and synthetic polymers, nanomaterials, and carbon-based nanomaterials, etc. In this chapter, we provide an overview of different types of materials used for biomedical applications, highlight the advancements in monolayer and multilayer coatings and discuss the techniques used to apply layered coatings to improve their characteristic features like biocompatibility, corrosion potential etc.
Materials that have been engineered to interact with biological systems for medical purposes are biomaterials. There are natural and synthetic biomaterials designed for biomedical applications such as supporting tissue regeneration, replacing or repairing damaged organs or tissues, delivering drugs or therapeutic agents to specific sites, supporting medical devices and implantations including orthopaedic implants, cardiovascular stents, dental implants, wound dressing, etc. Surface coatings are often used on biomaterials to enhance their biocompatibility, durability, functionality, and corrosion resistance in biomedical applications. These coatings can modify the surface properties of biomaterials to better suit their intended use and improve their interaction with biological systems. The implanting material must not cause any toxic, allergic or inflammatory reactions in the cells of the body. The degradability of the material should be neither too long nor too short; it should fulfill its purpose and then leave the body. To improve such features for a coating, materials with different advantages are integrated to create functionalised bilayer and multiple-layer coatings. The widely used materials in coatings are ceramic materials like hydroxyapatite, natural and synthetic polymers, nanomaterials, and carbon-based nanomaterials, etc. In this chapter, we provide an overview of different types of materials used for biomedical applications, highlight the advancements in monolayer and multilayer coatings and discuss the techniques used to apply layered coatings to improve their characteristic features like biocompatibility, corrosion potential etc.
A set of unique properties can be derived by a proper combination of organic and inorganic segments in a coating composition. The synthesis of such hybrid coatings is a challenging task due to that a number of variable parameters need to be optimized to achieve the desired results. Similar to the copolymerization of macromolecular segments in a common solvent, sol–gel chemistry could provide a viable alternate for the development of single-phase coating composition. The coating derived through sol–gel and wet chemistry displays homogenous physical and chemical characteristics. A large variety of chemical moieties containing labile functional groups are available for the development of new coating compositions. This article briefly reviews such studies that are reported in majority of the academic sector.
Water scarcity is still a pressing issue in many regions. The application of membrane technology through water desalination to convert brackish to potable water is a promising technology to solve this issue. This study compared the performance of templated TEOS-P123 and ES40-P123 hybrid membranes for brackish water desalination. The membranes were prepared by the sol–gel method by employing tetraethyl orthosilicate (TEOS) for the carbon-templated silica (soft template) and ethyl silicate (ES40) for the hybrid organo-silica. Both sols were templated by adding 35 wt.% of pluronic triblock copolymer (P123) as the carbon source. The silica-templated sols were dip-coated onto alumina support (four layers) and were calcined by using the RTP (rapid thermal processing) method. The prepared membranes were tested using pervaporation set up at room temperature (~25 °C) using brackish water (0.3 and 1 wt.%) as the feed. It was found that the hybrid membrane exhibited the highest specific surface area (6.72 m2·g−1), pore size (3.67 nm), and pore volume (0.45 cm3·g−1). The hybrid ES40-P123 was twice thicker (2 μm) than TEOS-P123-templated membranes (1 μm). Lastly, the hybrid ES40-P123 displayed highest water flux of 6.2 kg·m−2·h−1. Both membranes showed excellent robustness and salt rejections of >99%.
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