Low temperature syntheses of thioketals from enol ethers and carbonyl compounds

The effect of microwave on the interaction of flavour compounds with G‐actin from grass carp (Catenopharyngodon idella)

“…These binding sites have the capacity to react with volatile compounds, forming irreversible chemical binding and reversible bonding. Martel et al . reported that thiol groups on the surface of proteins could react with ketones and transform into dithioketals.…”

“…reported that the carboxyl group binds to proteins at the entrance to their central cavity. It has been demonstrated that ketones have the capacity to react with thiol groups and transform into dithioketals . Pérez‐Juan et al .…”

Diastereoselective formal total synthesis of (±)-triptolide via a novel cationic cyclization of 2-alkenyl-1,3-dithiolane

“…3). 17 This event delivers a highly electrophilic cation intermediate 15 which can be stabilized by mesomeric effect with the conjugated vinyl thionium ion 16 and the allylic carbenium ion 17. After electrophilic substitution of the aromatic ring and aromatization, thioenol 18 is formed, whose protonation by TfOH leads to sulfonium ion 19.…”

One-Pot, Highly Stereoselective Synthesis of Dithioacetal-α,α-Diglycosides

“…In the first step, TMSOTf promotes the highly diastereoselective (TMS) 2 S ring-opening of anhydrosugar A following a S N 2-type mode [ 6 ]. In a second step, addition of the resulting α-thioglycoside B to the TMSOTf-activated carbonyl compound affords the stabilized α-thio carbocation D via thioacetal C [ 15 , 16 , 17 , 18 ]. The subsequent interception of this carbocation by a second molecule of α-thioglycoside B affords the dithioacetal-α,α-diglycoside E after aqueous work-up.…”