Low-valent-tungsten catalysis enables hydroboration of esters and nitriles

Abstract

The research presented herein explores a low-valent-tungsten-catalyzed hydroboration of esters and nitriles. Both aromatic and aliphatic substrates were smoothly reduced to corresponding alcohol derivatives and N,N-diborylamines in the presence of...

Homogeneous Tungsten Catalysis for Controllable Selective Oxidation of Anilines via the W(O)(η2-O2)2 Intermediate

“…To make this tactic synthetically viable, certain preconditions should be satisfied: ( i ) the catalytic systems should be capable of navigating the oxidation network; ( ii ) they should selectively stop at a specific oxidation level; and ( iii ) they should tolerate other reactive functional groups embedded within the substrate. The focal point of our research program encompasses the study of molecular tungsten catalysis , and alkene functionalization. , Specifically, on the basis of previous literature studies − and our group’s explorations, , we have noted that ( i ) the W catalyst has the ability to adopt multiple coordination geometries and ( ii ) the center of W features high Lewis acidity compared to that of later transition metals, especially for high-valent tungsten. We envisaged that the unique configuration geometries and Lewis acidic properties of W(VI) complexes would be particularly beneficial in molecular (e.g., H 2 O 2 and O 2 ) activation.…”