2016
DOI: 10.1177/0003319716682121
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Lower Extremity Fibromuscular Dysplasia: Clinical Manifestations, Diagnostic Testing, and Approach to Management

Abstract: Fibromuscular dysplasia (FMD), a disease well described in the renal and cerebrovascular circulations, also manifests in the lower extremity (LE) arteries. This study reports on the clinical presentation, imaging findings, and treatment of patients with LE FMD seen at a single center. Over a 7-year span, 100 of 449 patients with FMD had imaging of the LE arteries, of which 62 were found to have LE FMD (13.8% of the entire FMD cohort including patients with and without LE imaging). The majority of patients were… Show more

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Cited by 11 publications
(10 citation statements)
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“…According to the recent registries, FMD involving the iliac arteries is present in 7%-62% of patients [9,11,12,14]. Most patients with lower extremity involvement are asymptomatic and may be diagnosed by femoral bruit noted on physical examination or incidentally on imaging studies.…”
Section: Iliac and Lower Extremity Fmdmentioning
confidence: 99%
See 2 more Smart Citations
“…According to the recent registries, FMD involving the iliac arteries is present in 7%-62% of patients [9,11,12,14]. Most patients with lower extremity involvement are asymptomatic and may be diagnosed by femoral bruit noted on physical examination or incidentally on imaging studies.…”
Section: Iliac and Lower Extremity Fmdmentioning
confidence: 99%
“…Surgery is reserved for complicated cases, progressive aneurysm growth following dissection or for treating complications of endovascular treatment. However, most patients are asymptomatic and can be managed conservatively including antiplatelet therapy [14].…”
Section: Treatmentmentioning
confidence: 99%
See 1 more Smart Citation
“…A total of 104 cases on iliac arterial FMD were reported (Table 1 ). [ 3 16 ] The mean age at diagnosis was 52.2 ± 12.6 years, and woman accounted for 86.5%. In terms of clinic presentation related to iliac arteries, 54 (51.9%) patients were asymptomatic, while 43 (41.3%) patients presented intermittent claudication or leg pain (an atypical symptom of claudication).…”
Section: Literature Reviewmentioning
confidence: 99%
“…[ 2 ] However, iliac arterial FMD was limited reported in case reports or series, and the demographic, clinical, and imaging features of iliac arterial FMD have not been precisely described. [ 3 16 ] We herein report the first man case of bilateral common and internal iliac arterial FMD in China, with renal artery involvement discovered by computed resonance angiography (CTA) and contaminant stenosis, aneurysm, and dissection, and then perform a literature review on iliac arterial FMD.…”
Section: Introductionmentioning
confidence: 99%