Aim: The purpose of this study was to compare the acute neuromuscular and metabolic responses between strength (S), hypertrophy (H), and power (P) resistance training protocols in the elbow flexors. Methods: Fourteen resistance trained men (age: 25 ± 4 years, body mass: 79.5 ± 9 kg, height: 177 ± 4cm) volunteered to participate. They attended four sessions separated by at least one week. On the first session, they performed a one repetition maximum (1RM) test for the standing barbell curl exercise. On the following three sessions, the training protocols were randomized to either a S (11 sets of 3 repetitions, 90% 1RM, 5-minute rest), H (4 sets of 10 repetitions, 75% 1RM, 90-second rest), or P (8 sets of 6 repetitions, 30% 1RM, 3-minute rest). Peak force (PF) and biceps brachii muscle activity (EMG) were quantified before and after each session via maximal voluntary isometric contraction of the elbow flexors. Blood samples were taken before and at 0, 3, 5, 10, 15 and 30 minutes after each session to measure the concentration of blood lactate (BL). Results: Higher total volume load (VL) in the S protocol compared to H (577.5±142.2 vs 568.5±133.3, P=0.03, respectively), and S compared to P (577.5±142.2 vs 294.8±67.5, P=0.001, respectively). Additionally, H showed higher VL compared to P (P=0.001). Conclusion: This study showed that the equated load between muscular strength and hypertrophy protocols compromised the neuromuscular and metabolic performance after single-joint exercise for upper limbs.