Lower Extremity Varicose Veins: An Unusual Presentation of Small Bowel Leiomyosarcoma

Joud, Karim Abou El; Abbasi, Misha

doi:10.1159/000520802

Cited by 3 publications

(2 citation statements)

References 16 publications

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“…Adjuvant chemotherapy can be explored in high-risk patients to lower the risk of local recurrence and improve survival rates, even if it is not universally acknowledged as the standard therapeutic plan for the postoperative care of adult patients with LMS (Gamboa, Gronchi, & Cardona, 2020). Treatment of leiomyosarcoma revolves around surgical excision of the tumor, and in this case, the patient had undergone an emergency laparotomy (Akwari et al, 1978), (Guzel et al, 2016), (Ashoor & Barefah, 2020), (Ahmed, 2020), (Garg et al, 2020), (Abou El Joud & Abbasi, 2022). Multiple enlarged mesenteric lymph nodes were noted around the jejunal tumor during surgery.…”

Section: Resultsmentioning

confidence: 99%

Acute Jejunal Leiomyosarcoma: A Rare Case Study

Essa Alfard

2023

Am. J. Med. Sci. Innov.

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The objective of this study is to describe a particular case example of small bowel leiomyosarcoma, which is characterized by an acute abdomen and signs and symptoms of intestinal obstruction. Sarcoma accounts for 1.2% of gastrointestinal malignancies. It can present as an asymptomatic mass or with constitutional symptoms like GI upset, melena, weight loss, fatigue, and rarely intussusception and bowel obstruction. Early diagnosis is difficult due to unspecified symptoms and the slow growth of the tumor. Surgical resection is still the preferred therapy. The case report was based on a 31-year-old gentleman hospitalized in the Emergency with severe abdominal aches, discomfort and nausea for 4 days. The patient had a significant unintentional weight loss for 1 month. A physical examination revealed epigastric and periumbilical tenderness. An immediate abdominal X-ray revealed several air-fluid levels, which indicate a minor intestinal obstruction in the core of the abdomen. A subsequent CT scan further noted an ileoileal intussusception with intestinal obstruction. The decision was taken to proceed with a crucial exploratory laparotomy, which reported a 4x5 cm tumor in the jejunum with several enlarged mesenteric lymph nodes. The histopathology report showed a high-grade leiomyosarcoma with confirmatory immunological staining.

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Section: Resultsmentioning

confidence: 99%

Acute Jejunal Leiomyosarcoma: A Rare Case Study

Essa Alfard

2023

Am. J. Med. Sci. Innov.

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“…The final diagnosis of LMS of the duodenum may have been fortuitous. The detection rates of LMSs are relatively low when using colonoscopy and esophagogastroduodenoscopy ( 16 ). Our current understanding of the imaging characteristics of LMS is limited due to the rarity of observing small bowel LMSs and the inadequacy of examinations.…”

Section: Discussionmentioning

confidence: 99%

Current landscape of primary small bowel leiomyosarcoma: cases report and a decade of insights

Zhou,

Xu,

et al. 2024

Front. Oncol.

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The incidence of leiomyosarcoma (LMS) is about 4–5/100,000 individuals per year. LMSs occurring in the small bowel are even rarer, and their preoperative diagnosis is very difficult. We described two patients with pathologically confirmed small bowel LMS and analyzed their clinical and medical imaging features. Similar cases reported in English in Pubmed database over the past decade were reviewed and summarized. These tumors were categorized by the growth direction and relationship with the intestinal lumen into three types: intraluminal (n = 10), intermural (n = 3), and extraluminal (n = 7). Notably, among the three types of LMS, the intramural leiomyosarcoma stands out as a noteworthy subtype. Emerging evidence suggests that smaller tumor size (< 5 cm) and the intraluminal type may serve as favorable prognostic indicators, while the extraluminal type is associated with relatively poor prognosis. Furthermore, the integration of imaging features with CA125 and LDH biomarkers holds promise for potential diagnostic value in LMS.

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Ileal leiomyosarcoma as a cause of small bowel obstruction

Pilipovic-Grubor,

Stojanovic,

Grdinic

et al. 2023

Srp Arh Celok Lek

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Introduction. Ileal leiomyosarcoma is unusual form of malignant gastrointestinal tumor. Often insidious in clinical presentation, it frequently presents a diagnostic challenge. Occasionally, a correct diagnosis is finally established due to emergency situation. The aim of this study is to present the role of magnetic enterography in determining the precise cause of small bowel dilation. Case outline. A 59-year-old female patient presented with small bowel obstruction. Erect abdominal radiograph identified the presence of small bowel obstruction and excluded pneumoperitoneum. Non-contrast computed tomography of the abdomen and pelvis noted transitional zone in the region of terminal ileum with collapsed bowel lumen distal to the transitional point, without determined underlying cause. Magnetic resonance enterography observed obstructive intraluminal soft-tissue mass with fatty component sized up to 4 cm in terminal ileum, with mesenteric involvement. The abdominal surgeon revealed ileal intraluminal tumor which affected the locoregional mesentery and serosa of the adjacent bowel. Histological and immunohistochemical analysis confirmed the diagnosis of ileal leiomyosarcoma with involvement of wall serosa and mesenteric fat tissue. Conclusion. Magnetic resonance enterography is a reliable diagnostic tool for detection and diagnosis of malignant small bowel tumors. Sometimes, tumors manifest clinically as bowel obstruction. Surgical treatment is necessary, while histology and immunohistochemistry are crucial to confirm the diagnosis of small bowel leiomyosarcoma.

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Lower Extremity Varicose Veins: An Unusual Presentation of Small Bowel Leiomyosarcoma

Cited by 3 publications

References 16 publications

Acute Jejunal Leiomyosarcoma: A Rare Case Study

Acute Jejunal Leiomyosarcoma: A Rare Case Study

Current landscape of primary small bowel leiomyosarcoma: cases report and a decade of insights

Ileal leiomyosarcoma as a cause of small bowel obstruction

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