Lower Gray Matter Density in the Anterior Cingulate Cortex and Putamen Can Be Traceable in Chronic Heroin Dependents after over 3 Months of Successful Abstinence

Keihani, Ahmadreza; Ekhtiari, Hamed; Batouli, Seyed Amir Hossein; Shahbabaie, Alireza; Seddighi, Nahid; Mirmohammad, Mahdieh; Oghabian, Mohammad Ali

doi:10.5812/iranjradiol.41858

Cited by 4 publications

(3 citation statements)

References 29 publications

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“…Details of our volumetric analysis methods were previously published Keihani et al, 2017). As a summary, initially, the quality of the T1-weighted scans was visually checked for a correct orientation and matrix size, for a proper signal to noise ratio, and no artifacts, using the Display toolbox, SPM12 (Welcome Department of Imaging Neuroscience: http:// www.fil.ion.ucl.ac.uk/spm), in MATLAB (version 9.0).…”

Section: Methodsmentioning

confidence: 99%

Larger Volume and Different Activation of the Brain in Response to Threat in Military Officers

Batouli

Saba

2020

BCN

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Introduction: Military missions involve stressful and life-threatening situations; however, soldiers should have a healthy cognition on the battlefield despite their high-stress levels. This is an ability that should be gained during prior military training. Successful and influential training is suggested to be associated with structural and functional improvements of the brain. Methods: This study investigated the pattern of brain activation while observing videos relevant to life-threatening situations, in addition to brain structure. Accordingly, the obtained data were compared between 20 military members and 26 healthy controls. The study participants were all male, aged between 19 to 24 years, right-handed, studying BSc, and from the same socioeconomic status. Results: The obtained data presented a larger volume in a total number of 1103 voxels of the brain (in 5 brain areas) in the military group. Furthermore, the military group suggested higher brain activation in the visual processing areas of the brain when observing real combat videos; however, this increment was mostly in the areas associated with motor processing and executive functions in the controls. Conclusion: This study indicated that military training is associated with positive structural changes in the brain. Besides, it provided a different brain activation in response to stressful situations. These findings highlighted the importance of qualified military training.

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Section: Methodsmentioning

confidence: 99%

Larger Volume and Different Activation of the Brain in Response to Threat in Military Officers

Batouli

Saba

2020

BCN

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“…Structural MRI such as diffusion tensor imaging helps assess Parkinson disease (Schwarz et al, 2014), Alzheimer disease (Kantarci et al, 2017), mesial temporal sclerosis (Corrêa et al, 2018), brain injury (Shenton, Price, Levin, & Edersheim, 2018), and for differentiating tumors and demyelinating diseases from normal tissues (Giussani et al, 2010). Similarly, volumetric MRI can help in distinguishing the addiction-related (Keihani et al, 2017) and sedentary lifestyle-related (Batouli & Saba, 2020) abnormalities of the brain, as well as in imaging genetics , schizophrenia (de Moura et al, 2018), migraine (Coppola et al, 2017), and epilepsy (Quan et al, 2017). The normative quantitative measures of the brain would act as the foundation for abnormality diagnosis purposes.…”

Section: Clinical Applicationsmentioning

confidence: 99%

Iranian Brain Imaging Database: A Neuropsychiatric Database of Healthy Brain

Batouli

Sisakhti

Haghshenas

et al. 2021

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Introduction: The Iranian Brain Imaging Database (IBID) was initiated in 2017, with 5 major goals: provide researchers easy access to a neuroimaging database, provide normative quantitative measures of the brain for clinical research purposes, study the aging profile of the brain, examine the association of brain structure and function, and join the ENIGMA consortium. Many prestigious databases with similar goals are available. However, they were not done on an Iranian population, and the battery of their tests (e.g. cognitive tests) is selected based on their specific questions and needs. Methods: The IBID will include 300 participants (50% female) in the age range of 20 to 70 years old, with an equal number of participants (#60) in each age decade. It comprises a battery of cognitive, lifestyle, medical, and mental health tests, in addition to several Magnetic Resonance Imaging (MRI) protocols. Each participant completes the assessments on two referral days. Results: The study currently has a cross-sectional design, but longitudinal assessments are considered for the future phases of the study. Here, details of the methodology and the initial results of assessing the first 152 participants of the study are provided. Conclusion: IBID is established to enable research into human brain function, to aid clinicians in disease diagnosis research, and also to unite the Iranian researchers with interests in the brain.

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“…The use of a substance can increase the reward system activity, leading to neglecting normal activities and appearing in some disorders, such as a cluster of cognitive, behavioral, and physiological symptoms [2]. Substance abuse causes damage to brain tissue [3][4][5][6][7] and its function [8][9][10]. In the electroencephalography (EEG) technique, recording the cortical activity by electrodes placed on the scalp led to providing the appropriate time resolution of brain activity in different mental states.…”

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confidence: 99%

Evaluation of Drug Abuse on Brain Function using Power Spectrum Analysis of Electroencephalogram Signals in Methamphetamine, Opioid, Cannabis, and Multi-Drug Abuser Groups

2023

J Biomed Phys Eng

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Background:The effect of different types of substances on brain function is still challenging; however, many studies have shown the functional and structural damage to the brain under influence of substance abuse.Objective: This study aimed to quantitatively compare the effect of opioid (Op), methamphetamine (Meth), cannabis (Can), and simultaneous methamphetamine and opioid (Multi-Drug (MD)) abuse on brain function. Furthermore, the impacts of pure Op and Meth abuse were considered with simultaneous substance abuse. Material and Methods:In this descriptive study, the electroencephalogram (EEG) signal was recorded from 52 participants in the Meth, Op, Can, and MD abusers, and the Healthy Control (HC) groups at rest state. EEG data were analyzed on the frequency domain with electrode-based, cortex-based, and hemisphere-based approaches.Results: However, the power spectrum in the delta band in the Op group, the gamma band in the Can group, and the gamma and beta bands in the MD group more significantly increased compared to the HC group, the power spectrum values in the Meth group reduced in the alpha, beta, and gamma bands. Moreover, the power spectrum values in the MD group more significantly higher than the Meth and Op groups in the beta and gamma bands. Conclusion:Since substance abuse in different types caused various changes in frequency components, the different power spectrum bands analysis in abusers can be reasonable to apply as a biomarker to detect the drug types.

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Lower Gray Matter Density in the Anterior Cingulate Cortex and Putamen Can Be Traceable in Chronic Heroin Dependents after over 3 Months of Successful Abstinence

Cited by 4 publications

References 29 publications

Larger Volume and Different Activation of the Brain in Response to Threat in Military Officers

Larger Volume and Different Activation of the Brain in Response to Threat in Military Officers

Iranian Brain Imaging Database: A Neuropsychiatric Database of Healthy Brain

Evaluation of Drug Abuse on Brain Function using Power Spectrum Analysis of Electroencephalogram Signals in Methamphetamine, Opioid, Cannabis, and Multi-Drug Abuser Groups

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