In the problem of unified classroom performance prediction, there is a certain lag in the prediction, and there are also problems such as the data sparsity and single feature in the data. In addition, feature engineering is often carried out manually in modeling, which highly depends on the professional knowledge and experience of engineers and affects the accuracy of the prediction to a certain extent. To solve the abovementioned gaps, we proposed an online course score prediction model with a high time efficiency that combines multiple features. The model uses a deep neural network, which can automatically carry out feature engineering and reduce the intervention of artificial feature engineering, thus significantly improving the time efficiency. Secondly, the model uses a factorization machine and two kinds of neural networks to consider the influence of first-order features, second-order features, and higher-order features at the same time, and it fully learns the relationship between the features and scores, which improves the prediction effect of the model compared to using only single feature learning. The performance of the model is evaluated on the learning analysis dataset from Fall 2015 to Spring 2021 and includes 412 courses with 600 students. The experimental results show that the performance of the prediction model based on the feature combination proposed in the present study is better than the previous performance prediction model. More importantly, our model has the best time efficiency of below 0.3 compared to the other models.