LSMO Nanoparticles Coated by Hyaluronic Acid for Magnetic Hyperthermia

Chen, Yuanwei; Wang, Ying; Liu, Xi; Lu, Mai; Cao, Jiangwei; Wang, Tao

doi:10.1186/s11671-016-1756-3

Cited by 23 publications

(7 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Also, according to the reported results by Hadimani et al [ 23 ], the accurate measurement of the Curie temperature with the line projection method under a 1 Tesla magnetic field is difficult, and by drawing a tangent line in the curve, the Curie temperature is obtained higher than the real value. Since, in the present study, the used magnetic field was 1000 Oe, a diagram of magnetization changes with temperature change (dM/dT) was drawn and T C was considered at the point where the dM/dT become zero to eliminate the effect of the applied magnetic field intensity [ 25 , 26 ] ( Figure 4 ).…”

Section: Resultsmentioning

confidence: 99%

Evaluation of Thermal Properties of Ferromagnetic Core for Treatment of Solid Tumors by Electromagnetic Induction Hyperthermia

2023

J Biomed Phys Eng

View full text Add to dashboard Cite

Background: Electromagnetic induction hyperthermia is a promising method to treat the deep-seated tumors such as brain and prostatic tumors. This technique is performed using the induction of electromagnetic waves in the ferromagnetic cores implanted at the solid tumor. Objective: This study aims at determining the conditions of the optimal thermal distribution in the different frequencies before performing the in vitro cellular study. Material and Methods: In this experimental study, the i-Cu alloy (70.4-29.6; wt%) was prepared and characterized and then the parameters, affecting the amount of induction heating in the ferromagnetic core, were investigated. Self-regulating cores in 1, 3, 6, and 9 arrangements in the water phantom with a volume of 2 cm 3 were used as a replacement for solid tumor. Results: Inductively Coupled Plasma (ICP) analysis and Energy Dispersive X-ray Spectroscopy (EDS) show the uniformity of the alloy after 4 times remeling by vacuum arc remelting furnace. The Vibrating Sample Magnetometer (VSM) shows that the Curie temperature (T C ) of the ferromagnetic core is less than 50 °C. Temperature profile with a frequency of 100-400 kHz for 30 min, was extracted by infrared imaging camera, indicating the increase temperature in the range of 42 °C to 46 °C. Conclusion: The optimum conditions with used hyperthermia system are supplied in the frequency of 100 kHz, 200 kHz and 400 kHz with 6, 3 and 1 seeds, respectively. It is also possible to induce a temperature up to 50 °C by increasing the number of seeds at a constant frequency and power, or by increasing the applied frequency at a constant number of seeds.

show abstract

Section: Resultsmentioning

confidence: 99%

Evaluation of Thermal Properties of Ferromagnetic Core for Treatment of Solid Tumors by Electromagnetic Induction Hyperthermia

2023

J Biomed Phys Eng

View full text Add to dashboard Cite

show abstract

“…applicable for magnetic hyperthermia treatment. Yuanwei Chen et al (2016) [33], synthesized and characterized nano-particle composite of lanthanum, strontium manganates. The Tc values of the particles were ranging from 43.9°C-49.2°C.…”

Section: Vibrating-sample Magnetometer (Vsm) Studiesmentioning

confidence: 99%

“…Specific loss power (SLP) is directly proportional to SAR values, which means that the amount of heat produced is directly proportional of the amount of magnetic radiation absorbed by the particles with respect to its mass. Whereas ESAR values are more specific to the type of coil diameter, current applied and the magnetic field strength used [33].…”

Section: Magnetic Hyperthermia Analysismentioning

confidence: 99%

Study of Viscoelastic Behaviour of Cellulose Fluid Carrying Iron Oxide Nanoparticles for Injectable In-Situ Hyperthermia Application

Ramadoss¹,

PB²,

Arivuoli³

et al. 2021

JMSSE

View full text Add to dashboard Cite

The current study deals with analysis of shear thinning and viscoelastic behaviour of cellulose fluid carrying iron oxide particles for injectable in-situ hyperthermia treatment. The iron oxide nano-particles of size 106 nm used in the study were synthesized through co-precipitation method using hydrothermal technique and were found to show high coercivity value of 75.83 Oe indicating its good stability. The magnetic nano-particles were suspended in a cellulose fluid for better injectability. This suspension along with the iron-oxide magnetic particles showed good heating efficiency of about 43 0 C in 60 seconds making it ideal for hyperthermia treatment. The specific absorption rate (SAR) and effective specific absorption rate (ESAR) were calculated for the as synthesized nano-particles and for suspension at varying concentrations and it was found that an optimized concentration of 20 mg of the nano-particles dispersed in 5 ml of the polymeric solution was ideal for hyperthermia treatment. The rheological properties studied for the suspension showed that the fluid showed shear-thinning and viscoelastic properties similar to that of human blood making it more suitable for carrying the iron-oxide nano-particles to the tumour site irrespective of the kind of shear stress that it is subjected to. The synthesized particles and the suspension fluid could successfully induce mild heat to the tumour site when delivered through intra-venous route or through intramuscular route thereby aiding radiotherapy and chemotherapy by dilating the blood vessels and thus enabling blood circulation to the poorly oxygenated cancer cells.

show abstract

“…HA-coated lanthanum strontium manganates (LSMO) have been studied with regards to their morphology, magnetic properties, and heating efficacy under AMF with different concentrations of each element. The HA-coated La 0.7 Sr 0.3 MnO 3 MNPs exhibited a heating temperature of 45.7 °C and a magnetic particle size of approximately 100 nm, indicating that they are suitable MNPs for mild hyperthermia [86].…”

Section: Magnetic Hyperthermia Treatmentmentioning

confidence: 99%

Biomedical Applications of Hyaluronic Acid-Based Nanomaterials in Hyperthermic Cancer Therapy

et al. 2019

View full text Add to dashboard Cite

Hyaluronic acid (HA) is a non-sulfated polysaccharide polymer with the properties of biodegradability, biocompatibility, and non-toxicity. Additionally, HA specifically binds to certain receptors that are over-expressed in cancer cells. To maximize the effect of drug delivery and cancer treatment, diverse types of nanomaterials have been developed. HA-based nanomaterials, including micelles, polymersomes, hydrogels, and nanoparticles, play a critical role in efficient drug delivery and cancer treatment. Hyperthermic cancer treatment using HA-based nanomaterials has attracted attention as an efficient cancer treatment approach. In this paper, the biomedical applications of HA-based nanomaterials in hyperthermic cancer treatment and combined therapies are summarized. HA-based nanomaterials may become a representative platform in hyperthermic cancer treatment.

show abstract

LSMO Nanoparticles Coated by Hyaluronic Acid for Magnetic Hyperthermia

Cited by 23 publications

References 22 publications

Evaluation of Thermal Properties of Ferromagnetic Core for Treatment of Solid Tumors by Electromagnetic Induction Hyperthermia

Evaluation of Thermal Properties of Ferromagnetic Core for Treatment of Solid Tumors by Electromagnetic Induction Hyperthermia

Study of Viscoelastic Behaviour of Cellulose Fluid Carrying Iron Oxide Nanoparticles for Injectable In-Situ Hyperthermia Application

Biomedical Applications of Hyaluronic Acid-Based Nanomaterials in Hyperthermic Cancer Therapy

Contact Info

Product

Resources

About