&lt;I&gt;Brain Metastasis from Transitional Cell Carcinoma of the Bladder&lt;/I&gt;

Wakisaka, Shinichiro; Miyahara, Satoshi; Nonaka, Akitsugu; Asami, Naoki; Kinoshita, Kazuo; Kohriyama, Kazuo

doi:10.2176/nmc.30.188

Cited by 8 publications

(9 citation statements)

References 12 publications

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“…Bladder cancer is commonly a disease of older age and is a common malignant disease of the urinary tract [1-4]. The Korea National Statistical Office reported that an estimated 3,230 new cases of bladder cancer occurred in 2008 in Korea with 1,007 deaths.…”

Section: Discussionmentioning

confidence: 99%

“…Babaian et al [5] reported that evidence of metastatic disease was found in a postmortem examination in approximately two thirds of patients with bladder cancer. The incidence of clinically detected distant metastases from urothelial carcinoma of the bladder reportedly ranges from 9.5% to 29% [1,6]. Lymph nodes, liver, lung, bone, and peritoneum are the most common metastatic sites of urothelial carcinoma of bladder, whereas skin, brain, heart, and kidney are rarely involved [1-3].…”

Section: Discussionmentioning

confidence: 99%

“…The incidence of clinically detected distant metastases from urothelial carcinoma of the bladder reportedly ranges from 9.5% to 29% [1,6]. Lymph nodes, liver, lung, bone, and peritoneum are the most common metastatic sites of urothelial carcinoma of bladder, whereas skin, brain, heart, and kidney are rarely involved [1-3]. Only 7 cases of skin metastasis from bladder cancer have been reported in Korea [7].…”

Section: Discussionmentioning

confidence: 99%

“…According to the Brain Tumor Registry of Japan, only 0.6% of metastatic brain tumors were from bladder cancers [8]. In another study, central nervous system metastases were found in fewer than 1% of cases [1]. Urothelial carcinoma metastasizes to the brain hematogenously, and cancer cells are filtered by the lungs.…”

Section: Discussionmentioning

confidence: 99%

“…Bladder cancer has variable metastatic potential and almost any organ can be involved by metastasis. Lymph nodes, liver, lung, and bone are the most common metastatic sites of urothelial carcinoma of the bladder, with skin, brain, heart, and kidney being rare sites of metastasis [1-3]. We report a case of urothelial carcinoma of the bladder with brain and abdominal skin metastasis.…”

Section: Introductionmentioning

confidence: 99%

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Brain and Skin Metastasis From Urothelial Carcinoma of the Bladder

et al. 2013

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Brain and skin metastasis from urothelial carcinoma of the bladder is rare. There have been few case reports of the clinical course of patients with metastatic urothelial carcinoma of the brain and skin. In the present case, a 60-year-old man had undergone radical cystectomy with an ileal conduit owing to urothelial carcinoma (T1N0M0). The patient developed dizziness 9 years later and a solitary brain tumor was discovered in his left cerebellar hemisphere. The tumor was totally resected and the mass was verified to be metastatic urothelial carcinoma. One year after the metastasectomy of the brain lesion, multiple erythematous nodular lesions developed on his abdominal skin. The skin lesions were excised and verified to be metastatic urothelial carcinoma. This report describes this case of urothelial carcinoma of the bladder that metastasized to the brain and abdominal skin.

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Section: Discussionmentioning

confidence: 99%