2006
DOI: 10.1248/bpb.29.1906
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<i>In Vitro</i> Antioxidant Studies on the Benzyl Tetra Isoquinoline Alkaloid Berberine

Abstract: Berberine is a benzyl tetra isoquinoline alkaloid which is widely used as an antimicrobial and an antidiarrhoeal. As berberine containing plants are virtually used in all forms of traditional medicine, our study aimed to examine the antioxidant activity of berberine using 2,2-diphenyl 1-picrylhydrazyl (DPPH) radical scavenging, nitric oxide scavenging, lipid peroxidation, superoxide scavenging, iron chelating activity and 2,2-azino bis(3-ethylbenzothiazoline-6-sulfonate) (ABTS) radical scavenging methods. The … Show more

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Cited by 293 publications
(184 citation statements)
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“…Lipid peroxidation inhibition was determined by Shirwaikar et al, [22] . Ascorbic acid and trolox was used for comparison.…”
Section: Reducing Power and Lipid Peroxidation Inhibitionmentioning
confidence: 99%
“…Lipid peroxidation inhibition was determined by Shirwaikar et al, [22] . Ascorbic acid and trolox was used for comparison.…”
Section: Reducing Power and Lipid Peroxidation Inhibitionmentioning
confidence: 99%
“…ABTS also forms a relatively stable free radical, which decolorizes in its nonradical form [41]. The spectrophotometric analysis of ABTS zþ scavenging activity was determined according to the method of Re and co-workers [42].…”
Section: Abts Radical Cation Decolorization Assaymentioning
confidence: 99%
“…The relative abilities of antioxidants to scavenge ABTS radical cation (ABTS •+ ) were measured by comparison with the antioxidant potency of standard amounts of trolox (6-hydroxy-2, 5, 7, 8-tetramethyl chroman-2-carboxylic acid) following the method of Shirwaikar et al, 22 ABTS •+ was prepared by a reaction between 5 mL of 0.0192 g of ABTS…”
Section: Antioxidant Activity Abts Radical Scavenging Activitymentioning
confidence: 99%