&lt;i&gt;Indigofera tinctoria&lt;/i&gt; Linn (Fabaceae) attenuates cognitive and behavioral deficits in scopolamine-induced amnesic mice

Kim, Jong-Bo; Kopalli, Spandana Rajendra; Koppula, Sushruta

doi:10.4314/tjpr.v15i4.15

Cited by 3 publications

(2 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Indigofera -the plant that gives "indigo" dye belongs to the leguminous family and has about 800 species [1].…”

Section: Methodsmentioning

confidence: 99%

“…When studying the effect of the Indigofera plant on soil salinity in improving the productivity of degraded soils in the soil-climatic conditions of Khorezm region, the indicators of the dynamics of the reduction of salts in the soil were chlorine ion -0.037%; It was observed that SO4 -0.0028%, dry residue decreased to 0.01% and pH decreased to 0.07% [1].…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Effect of stimulants to photosynthetic and symbiotic activity of indigofera tinctoria L. Plant

Yakubov,

Negmatova,

Nurullaeva

et al. 2024

E3S Web Conf.

View full text Add to dashboard Cite

The article describes the application period and standards of various stimulants on photosynthetic and symbiotic activity of the nontraditional leguminous plant Indigofera (Indigofera tinctoria L.) during its cultivation in the conditions of the meadow alluvial soils of the Khorezm region of the northern are of Republic of Uzbekistan. When Indigofera is applied with Geohumat stimulator for at the rate of 1.0 l/t along with planting and 1.6 l/ha during the 3-4 true leaves and pruning periods of the growing season, the intensity of development increased, and it has been substantiated that the area of the leaf surface in one plant was 3675.0 cm2, compared to the control variant without the stimulant was 1286.3 cm2/plant. and 397.5 cm2/plant compared to the variant where Geohumat stimulator was used only with planting, photosynthetic potential has increased up to 92766.0 cm2/plant. In addition, when Geohumat stimulator is applied at acceptable rates along with planting and during the period of 3-4 true leaves of the growing season, up to 70 nodular bacteria are formed in one Indigofera root, and its positive effect on improving soil fertility is explained.

show abstract

“…Indigofera -the plant that gives "indigo" dye belongs to the leguminous family and has about 800 species [1].…”

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Effect of stimulants to photosynthetic and symbiotic activity of indigofera tinctoria L. Plant

Yakubov,

Negmatova,

Nurullaeva

et al. 2024

E3S Web Conf.

View full text Add to dashboard Cite

show abstract

Piperine abates cognitive dysfunction via modulation of key enzymes relevant to neurodegeneration in scopolamine-induced rats

2023

View full text Add to dashboard Cite

Therapeutic potential of Bhiramiyadhi bhavanai choornam in ameliorating scopolamine-induced impaired learning and memory in rats: neuroprotective effects and mechanistic insights

S. Bhosale,

Sivakkumar,

Jamadagni

et al. 2024

RJPT

View full text Add to dashboard Cite

This study intended to explore Bhiramiyadhi bhavanai choornam’s (BBC) effect on scopolamine-induced impaired learning and memory in rats. BBC was prepared and subjected to organoleptic and phytochemical investigations. Scopolamine (2mg/kg, i.p.) was injected into all animals except for the vehicle control group. Donepezil 1mg/kg and BBC (215, 430, and 860mg/kg along with a 1:1 ratio of ghee and honey) were administered orally for 14 days to respective groups. The effect of BBC on locomotor activity, olfactory and spatial memory and exploratory behaviour was evaluated. Later, animals were sacrificed, and brain homogenates were tested for levels of malondialdehyde, antioxidant enzymes, acetylcholinesterase, nitric oxide and TNF-α. A statistical evaluation was carried out. Investigating BBC for phytoconstituents, showed that steroids, phenols, tannins, quinones, alkaloids, flavonoids, glycosides, terpenoids and carbohydrates were present. Treatment with BBC reversed scopolamine-induced learning and memory impairment by significantly (p < 0.001) improving behaviour in the Y maze, novel object recognition test and MWM. BBC also decreased oxidative stress induced by scopolamine by increasing reduced levels of antioxidant enzymes and declining MDA, AChE, NO, and TNF- α levels in the rat brain in a rat model of scopolamine-induced learning and memory impairment.

show abstract

<i>Indigofera tinctoria</i> Linn (Fabaceae) attenuates cognitive and behavioral deficits in scopolamine-induced amnesic mice

Abstract: Purpose: To investigate the cognition-enhancing effects of aqueous extract of Indigofera tinctoria Linn (ITE, Fabaceae)

Cited by 3 publications

References 18 publications

Effect of stimulants to photosynthetic and symbiotic activity of indigofera tinctoria L. Plant

Effect of stimulants to photosynthetic and symbiotic activity of indigofera tinctoria L. Plant

Piperine abates cognitive dysfunction via modulation of key enzymes relevant to neurodegeneration in scopolamine-induced rats

Therapeutic potential of Bhiramiyadhi bhavanai choornam in ameliorating scopolamine-induced impaired learning and memory in rats: neuroprotective effects and mechanistic insights

Contact Info

Product

Resources

About