&lt;p&gt;Choroidal Cavitary Disorders&lt;/p&gt;

Nassar, Sandra; Tarbett, Aaron K.; Browning, David J.

doi:10.2147/opth.s264731

Cited by 10 publications

(5 citation statements)

References 116 publications

(376 reference statements)

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“…22 Macular ICC has also been reported in other conditions such as North Carolina macular dystrophy, and torpedo maculopathy. 23 In contrast to axial elongation hypothesized to be the cause of cavitations in high-myopia, the underlying mechanism for macular ICC formation in the aforementioned diseases is thought to be congenital. However, the mechanism of macular ICC in non-myopic eyes with or without FCE remains unclear.…”

Section: Discussionmentioning

confidence: 99%

Multimodal imaging of focal choroidal excavation and macular choroidal cavitation associated to choroidal neovascularization

El Matri,

Saidane,

Bouazzaoui

et al. 2023

European Journal of Ophthalmology

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Purpose: To report multimodal imaging features of an unusual case of multiple focal choroidal excavations (FCE) associated to macular intrachoroidal cavitations (ICC) and choroidal neovascularization (CNV) in a non-myopic patient with normal choroidal thickness. Methods: Observational case report. Results: A 69-year-old non-myopic male patient with history of macular CNV of unknown etiology in the right eye (RE), initially treated with Bevacizumab intravitreal injections with significant improvement of visual acuity. He presented with acute vision loss in the same eye related to recurrent CNV exudation. Multimodal imaging of the RE confirmed the diagnosis of active type 2 CNV, associated to multiple FCE. Besides, it highlighted incidental unusual macular ICC in the same eye. Choroidal thickness was within normal limits (217 μm). Conclusion: Focal choroidal excavations and intrachoroidal cavitations can be observed in emmetropic patients in the absence of pachychoroid disease. In presence of CNV of unknown etiology, complete multimodal imaging can be of a great help to better define choroidal anomalies, allowing structural and vascular correlations between different lesions. Key words: Focal choroidal excavation; Choroidal cavitation; Multimodal imaging

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Section: Discussionmentioning

confidence: 99%

Multimodal imaging of focal choroidal excavation and macular choroidal cavitation associated to choroidal neovascularization

El Matri,

Saidane,

Bouazzaoui

et al. 2023

European Journal of Ophthalmology

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“…PCA severely impacts vision due to the absence of underlying choroid and the degeneration of overlying RPE and photoreceptors. [ 7 , 9 ] The progression and expansion of these lesions is the leading cause of vision loss in pathological myopia. [ 6 ] Consequently, BCVA decreased from 20/20 to 20/100 during the follow-up period in our case.…”

Section: Discussionmentioning

confidence: 99%

“…Additionally, the retina thinned, which resulted in deviation into the ICC. PCA severely impacts vision due to the absence of underlying choroid and the degeneration of overlying RPE and photoreceptors [7,9] . The progression and expansion of these lesions is the leading cause of vision loss in pathological myopia [6] .…”

Section: Discussionmentioning

confidence: 99%

Four-year follow up of macular intrachoroidal cavitation and chorioretinal atrophy

Abe

Iwase

2021

Medicine

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Rationale: Macular intrachoroidal cavitation (ICC) is characterized by presence of a hyporeflective space beneath the unaltered retinal pigment epithelium (RPE) and is noted around the region of focal chorioretinal atrophy in eyes with pathologic myopia. The findings suggest that the patchy chorioretinal atrophy (PCA) progresses to ICC with time. However, there have been no reports describing long-term observational studies using OCT. We collected a case of PCA progression to macular ICC using OCT during a 4-year follow-up. Patient concerns: A 65-year-old woman presented with metamorphopsia and blurred vision in her left eye. Her best-corrected visual acuity (BCVA) was 20/20 and spherical equivalent refraction was –14.0 diopters in the left eye. Fundus examination revealed a white, well-defined PCA at the superonasal to the fovea which showed hypofluorescence determined by autofluorescence in the left eye. Sclera curved posteriorly at the superonasal to the fovea and the choroid was thickened at the area and ellipsoid zone (EZ) was disrupted in the area in OCT images. Additionally, another OCT images through the PCA showed a disappearance of the RPE–Bruch's membrane complex and a connection of blood vessels running from the sclera to the choroid. Diagnoses: PCA with macular ICC. Interventions: Observation. Outcomes: During 4-year follow up, the white patchy lesion and the hypofluorescence region gradually expanded. BCVA decreased with the expansion of the lesion and was 20/100 at the final visit. OCT through the fovea showed that the disorganized EZ expanded toward the ICC and the sensory retina of the fovea became thinner. Moreover, RPE–Bruch's membrane complex was not observed 3 years after the initial visit. During the follow-up period, the sensory retina was prominently displaced posteriorly to the ICC, though no obvious change was observed in the structure of the sclera. Lessons: In cases of PCA with macular ICC, the outer retina and RPE may initially atrophy, showing as an expansion of PCA, because the attachment between the inner retina and sclera may be weakened. This may result in the displacement of the retinal tissue into the space of macular ICC.

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“…Myopic choroidal cavitations (MCCs) are described in eyes with pathological myopia and are frequently located in the peripapillary areas and at the borders of staphylomas 1 2. On SD-OCT, they appear as hyporeflective spaces beneath the unaltered RPE layer.…”

Section: Descriptionmentioning

confidence: 99%

Extensive peripapillary and macular myopic choroidal cavitations in a young myope

Nagesha,

Venkatesh,

Gandhi

et al. 2024

BMJ Case Rep

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<p>Choroidal Cavitary Disorders</p>

Cited by 10 publications

References 116 publications

Multimodal imaging of focal choroidal excavation and macular choroidal cavitation associated to choroidal neovascularization

Multimodal imaging of focal choroidal excavation and macular choroidal cavitation associated to choroidal neovascularization

Four-year follow up of macular intrachoroidal cavitation and chorioretinal atrophy

Extensive peripapillary and macular myopic choroidal cavitations in a young myope

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