&lt;p&gt;Clinical factors influencing resilience in patients with anorexia nervosa&lt;/p&gt;

Kane, Chikako; Tomotake, Masahito; Hamatani, Sayo; Chiba, Shinichi; Kameoka, Naomi; Watanabe, Shinya; Nakataki, Masahito; Numata, Shusuke; Ohmori, Tetsuro

doi:10.2147/ndt.s190725

Cited by 7 publications

(3 citation statements)

References 28 publications

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“…Moreover, resilience may predict the individuals’ ability to improve when presented with adverse life difficulties [ 59 ]. In line with our findings, previous studies have also found lower resilience in patients with AN compared to control participants, associating this finding with the presence of interoceptive confusion, interpersonal difficulties, negative self-image, and ineffectiveness in patients with AN, as well as with an influence of the ED-related pathology per se [ 60 , 61 ].…”

Section: Discussionsupporting

confidence: 92%

The emotional-behavioral state of Israeli adolescent and young adult females with anorexia nervosa during the COVID19 pandemic

et al. 2022

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Background During the COVID-19 pandemic in Israel, the number of patients with eating disorders (EDs) seeking treatment increased significantly. The present study sought to evaluate whether, during the pandemic (2020–21), patients with anorexia nervosa (AN) would show more ED-related, comorbid, and COVID-19-related symptoms in comparison to a naturalistic control group, and whether differences would be found between adult and adolescent patients with AN. We also examined attitudes to telemedicine use during the pandemic in patients receiving long-distance interventions. Methods Using online self-report questionnaires, we assessed general and COVID-19-specific symptoms with a secure digital platform (REDCap®) in 36 female adolescents with AN, 35 female adults with AN, and 25 female controls. Results Compared with controls, patients with AN showed more symptoms of EDs, anxiety, depression, and post-traumatic stress disorder (PTSD), elevated suicidal ideation, more COVID-related emotional-behavioral disturbances, and lower resilience. Adult patients with AN fared worse than adolescent patients on most of these measures. Adult patients using telemedicine during the COVID-19 pandemic showed fewer positive attitudes toward this treatment than adolescents (telemedicine was offered to all, but used by 18/35 adolescents and 21/36 adults with AN). Last, elevated COVID-19-related symptomatology was correlated with more symptoms of ED, anxiety, depression and PTSD, and with lower resilience. Conclusions Our findings suggest that the emotional-behavioral state of Israeli females with AN, particularly adults, was worse during the COVID-19 pandemic in comparison to controls. Many patients did not use telemedicine for their treatment. Adult patients using telemedicine were less satisfied with it than adolescent patients.

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Section: Discussionsupporting

confidence: 92%

The emotional-behavioral state of Israeli adolescent and young adult females with anorexia nervosa during the COVID19 pandemic

et al. 2022

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“…The common feature of resilience manifests in its dynamic nature, i.e., the ability of a system (e.g., a material, a plant, or a brain) exposed to a harmful stimulus to absorb, accommodate or adapt to the effects of the stress in an efficient manner by adjusting its structure, organization, physiological mechanisms, metabolic regulation, mode of action, etc. The resilience phenomenon is also commonly observed in human neurological diseases, particularly in neurodegenerative and neuropsychiatric diseases 11,[16][17][18][19][20] . Despite exposure to traumatic events or even to the presence of advanced pathophysiological changes, some people do not exhibit behavioral and psychological symptoms.…”

Section: Introductionmentioning

confidence: 99%

Stress resilience is an active and multifactorial process manifested by structural, functional, and molecular changes in synapses

Bączyńska

Zaręba-Kozioł

Ruszczycki

et al. 2022

Preprint

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Stress resilience is the ability of neuronal networks to maintain function despite exposure to stress. In this study, we investigated whether stress resilience is an actively developed dynamic process in adult mice. To assess the resilient and anhedonic behavioral phenotypes developed after induction the chronic unpredictable stress, we quantitatively characterized the structural and functional plasticity of excitatory synapses in the hippocampus using a combination of proteomic, electrophysiological, and imaging methods. Our results indicate that stress resilience is a dynamic and multifactorial process manifested by structural, functional, and molecular changes in synapses. We reveal that chronic stress influences palmitoylation, the profiles of which differ between resilient and anhedonic animals. We also observed that stress resilience is associated with structural compensatory plasticity of the postsynaptic parts of synapses.One Sentence SummaryCompensatory remodeling of dendritic spines at the structural and molecular levels underlies stress resilience.

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“…The literature supports an association between negative self-image, feelings of being rejected by others, and resilience among patients with anorexia nervosa. 3 There is also evidence from a clinical population of adolescents that body size dissatisfaction is a predictor of low resilience. 4 In a qualitative study of adults recovering from EDs, authors suggest a multilevel resilience framework as a potential strategy for treatment and recovery.…”

Section: Introductionmentioning

confidence: 99%

Effect of Strength-Based Resilience on Patient's Length of Stay at the Renfrew Center for Eating Disorders

Sanzone

Short

Gaughan

et al. 2022

Women's Health Reports

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Objective: Throughout past decades, physicians have sought to understand factors that contribute to severity of an eating disorder (ED). There is a potential relationship between patients' resilience and the recovery course of their disorder. The objective of this study is to examine the correlation between resilience, measured by indicators of mindfulness and restraint, and length of stay (LOS) at Renfrew Center for Eating Disorders. Materials and Methods: Data were obtained from Renfrew's database. Secondary analysis was conducted from this database. The database included women aged 13–75 years admitted to Renfrew. The database excluded males and individuals of ages <13 or >75 years old. Resilience was analyzed through Southampton Mindfulness Questionnaire (SMQ) and ED restraint. The dependent variable, LOS at Renfrew, was analyzed by multivariable linear regression, and multivariable logistic regression for LOS >45 days. Results: A sample of 2901 subjects was analyzed. There were significant associations between increased mindfulness scores and decreased restraint scores and a decreased LOS at Renfrew. For every 13-point increase in SMQ, the LOS was associated with a decrease by ∼1 day, and for every 1-point decrease in the restraint score (increased restraint), the LOS was associated with a decrease by ∼1 day. Higher restraint scores were independently associated with an increase in likelihood of LOS >45 days by 22.8%. Conclusions: The Renfrew data support the relationship between a patient's resilience and LOS. This information holds promise for future treatment approaches to improve strength-based modalities in patients suffering from EDs.

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<p>Clinical factors influencing resilience in patients with anorexia nervosa</p>

Cited by 7 publications

References 28 publications

The emotional-behavioral state of Israeli adolescent and young adult females with anorexia nervosa during the COVID19 pandemic

The emotional-behavioral state of Israeli adolescent and young adult females with anorexia nervosa during the COVID19 pandemic

Stress resilience is an active and multifactorial process manifested by structural, functional, and molecular changes in synapses

Effect of Strength-Based Resilience on Patient's Length of Stay at the Renfrew Center for Eating Disorders

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