&lt;p&gt;Efficacy and Safety of Electroacupuncture for Insomnia Disorder: A Multicenter, Randomized, Assessor-Blinded, Controlled Trial&lt;/p&gt;

Lee, Boram; Kim, Hyeong-Jun; Jung, In Chul; Kim, Ae‐Ran; Park, Hyo-Ju; Kwon, Ojin; Lee, Jun-Hwan; Kim, Joohee

doi:10.2147/nss.s281231

Cited by 18 publications

(9 citation statements)

References 59 publications

(94 reference statements)

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“…In the present study, the impact of pain on all considered activities and quality of life aspects was found to be significantly decreased after the acupuncture treatment and in the short-term follow-up in all three study groups, except for the aspect of “walking ability.” In particular, electroacupuncture was found to be effective in improving the influence of pain on the patient's quality of sleep and mood, with a statistically significant difference compared to body acupuncture and acupuncture combined with cupping. These results are consistent with the evidence defining EA as an effective therapeutic intervention for patients with anxiety, depression, and primary insomnia, capable of improving patients' life and sleep quality without serious adverse effects [ 37 – 41 ]. A multidisciplinary therapeutic approach is needed to address all factors, including sleep and mood alterations, which modulate pain experience.…”

Section: Discussionsupporting

confidence: 89%

Comparison of the Effectiveness of Three Different Acupuncture Methods for TMD-Related Pain: A Randomized Clinical Study

Serritella

Galluccio

Impellizzeri

et al. 2021

Evidence-Based Complementary and Alternative Medicine

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Purpose. This study aimed to compare the effectiveness of three acupuncture methods for temporomandibular disorders- (TMDs-) related pain. Materials and Methods. Different locations of pain, according to DC/TMD clinical assessment, were considered: temporomandibular joint (TMJ), masticatory muscles, head, and neck. Sixty patients were assigned randomly to one of three treatment groups (20 patients in each): group BA received body acupuncture, group EA received electroacupuncture, and group CA received acupuncture + cupping. The groups were compared in terms of pain (verbal numeric scale), pain-related disability (Brief Inventory Pain, BPI), and impression of the treatment’s effectiveness (Patients' Global Impression of Improvement Scale, PGI-I). These were recorded before sessions of acupuncture treatment (T0), after 8 sessions of acupuncture treatment (T1), and after 4 weeks of follow-up after treatment (T2). The between-group and within-group differences in the data were analyzed statistically. The baseline characteristics were similar in all groups ( p > 0.05 ). Results. Significant improvements were noted in all types of pain compared to baseline values in all groups (all p < 0.05 ). No significant differences were noted in the improvement of TMDs-related pain according to the different acupuncture techniques (all p > 0.05 ). All acupuncture methods used resulted to be significantly effective in improving the pain-related interference in the patient’s common activities and quality of life. EA resulted to be significantly more effective than BA and CA in improving the interference of pain with patients’ mood ( p = 0.015 ) and quality of sleep ( p = 0.014 ). Conclusion. BA, EA, and CA are all effective acupuncture methods in reducing pain and pain interference with common activities and quality of life in patients affected by TMD.

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Section: Discussionsupporting

confidence: 89%

Comparison of the Effectiveness of Three Different Acupuncture Methods for TMD-Related Pain: A Randomized Clinical Study

Serritella

Galluccio

Impellizzeri

et al. 2021

Evidence-Based Complementary and Alternative Medicine

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“…(2013) [ 155 ] CBTi CBTi (self-help) Anxiety HADS-A 102 95 −0.16 Depression CES-D 102 95 −0.32∗ Lee et al. (2020) [ 156 ] Acupuncture WLC Depression HADS-D 49 49 −2.66∗∗∗ Anxiety HADS-A 49 49 −0.91∗∗∗ Lichstein et al. (2013) [ 157 ] CBTi Hypnotic taper Anxiety STAI 22 18 −0.35 Depression GDS 22 18 −0.72∗ Martinez et al.…”

Section: Methodsmentioning

confidence: 99%

Improving sleep quality leads to better mental health: A meta-analysis of randomised controlled trials

Scott

Webb

James

et al. 2021

Sleep Medicine Reviews

468

231

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The extent to which sleep is causally related to mental health is unclear. One way to test the causal link is to evaluate the extent to which interventions that improve sleep quality also improve mental health. We conducted a meta-analysis of randomised controlled trials that reported the effects of an intervention that improved sleep on composite mental health, as well as on seven specific mental health difficulties. 65 trials comprising 72 interventions and N = 8,608 participants were included. Improving sleep led to a significant medium-sized effect on composite mental health (g+ = -0.53), depression (g+ = -0.63), anxiety (g+ = -0.51), and rumination (g+ = -0.49), as well as significant small-to-medium sized effects on stress (g+ = -0.42), and finally small significant effects on positive psychosis symptoms (g+ = -0.26). We also found a dose response relationship, in that greater improvements in sleep quality led to greater improvements in mental health. Our findings suggest that sleep is causally related to the experience of mental health difficulties. Future research might consider how interventions that improve sleep could be incorporated into mental health services, as well as the mechanisms of action that explain how sleep exerts an effect on mental health.

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“…Therefore, we suggest shortening this period to 1 month in future studies, on the basis of a recent related study [ 55 ]. According to a recent clinical trial targeting the general insomnia population, in which EA was performed 10 times for 4 weeks similar to this study, a total of 150 participants were enrolled over 9 months in 4 Korean medicine hospitals [ 56 ]. Taking this into account, the participant recruitment in our study seems to have been very slow because our study was conducted with people with cancer.…”

Section: Discussionmentioning

confidence: 99%

Electroacupuncture for treating cancer-related insomnia: a multicenter, assessor-blinded, randomized controlled, pilot clinical trial

Lee

Kim

et al. 2022

BMC Complement Med Ther

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Background Insomnia is one of the most frequent symptoms in people with cancer. Electroacupuncture has been widely used in people with cancer or insomnia. We explored the feasibility and preliminary effectiveness of electroacupuncture for cancer-related insomnia. Methods People with cancer and insomnia disorder were randomly allocated to electroacupuncture, sham-electroacupuncture, or usual care groups. Participants received either 10 sessions of electroacupuncture at real acupoints, sham-electroacupuncture at non-acupoints, or usual care in each group for 4 weeks. We calculated the recruitment, adherence, and completion rates of participants. The Insomnia Severity Index (ISI), Pittsburgh Sleep Quality Index (PSQI), sleep diary and actigraphy-derived sleep parameters, Functional Assessment of Cancer Therapy-Fatigue (FACT-F), Montreal Cognitive Assessment (MoCA), and salivary levels of cortisol and melatonin were evaluated as outcome measures. Results Twenty-two participants were enrolled (8, 6, and 8 respectively in the electroacupuncture, sham-electroacupuncture, and usual care groups) and 20 participants completed the trials (8, 4, and 8 respectively). The recruitment, adherence, and completion rates were 78.57% (22/28), 95.45% (21/22), and 90.91% (20/22), respectively. Most of the participants had previously received conventional treatment for insomnia, but few had received Korean medicine treatment, without any demographic or clinical differences between groups. In the electroacupuncture group, there was a statistically significant reduction of 10.13 (mean) ± 8.15 (standard deviation) and 5 ± 3.70 points in mean ISI and PSQI scores at 4 weeks post-treatment (P = .0098 and .0066), compared with sham-electroacupuncture (2.06 ± 7.15 and 1.61 ± 4.34; P = .4796 and .3632) and usual care (3.25 ± 2.60 and 1.38 ± 2.13; P = .0096 and .1112). Although there was no significant difference in ISI score between groups at 4 weeks post-treatment, the electroacupuncture group continued to improve significantly at 4 weeks’ follow-up, showing borderline and significant differences compared to the sham-electroacupuncture and usual care (P = .0614 and .0015). The FACT-F scores in electroacupuncture group showed a significant improvement compared with the sham-electroacupuncture group (P = .0305). No electroacupuncture-related adverse events were reported. Conclusions Electroacupuncture might be feasible for cancer-related insomnia, despite slow participant recruitment. Additional trials with adequately powered sample sizes and a substantial change to the recruitment procedure are needed. Trial registration Clinical Research Information Service, KCT0002162. Submitted 27 October 2016, Registered 2 December 2016 - Retrospectively registered (The first participant enrolment: 28 November 2016),

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<p>Efficacy and Safety of Electroacupuncture for Insomnia Disorder: A Multicenter, Randomized, Assessor-Blinded, Controlled Trial</p>

Cited by 18 publications

References 59 publications

Comparison of the Effectiveness of Three Different Acupuncture Methods for TMD-Related Pain: A Randomized Clinical Study

Comparison of the Effectiveness of Three Different Acupuncture Methods for TMD-Related Pain: A Randomized Clinical Study

Improving sleep quality leads to better mental health: A meta-analysis of randomised controlled trials

Electroacupuncture for treating cancer-related insomnia: a multicenter, assessor-blinded, randomized controlled, pilot clinical trial

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