2020
DOI: 10.2147/ndt.s231573
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<p>Electroconvulsive Therapy for Patients with Catatonia: Current Perspectives</p>

Abstract: Catatonia is a serious, common syndrome of motoric and behavioral dysfunction, which carries high morbidity and mortality. Electroconvulsive therapy (ECT) is the definitive treatment for catatonia, but access to ECT for the treatment of catatonia remains inappropriately limited. Catatonia is observable, detectable, and relevant to various medical specialties, but underdiagnosis impedes the delivery of appropriate treatment and heightens risk of serious complications including iatrogenesis. Current understandin… Show more

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Cited by 65 publications
(37 citation statements)
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References 200 publications
(325 reference statements)
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“…Catatonia is a potentially life-threatening, motor syndrome, characterized by mental and physical immobilization and stereotypic behaviors, which may alternate with agitation and complicated with rigidity, hyperthermia and autonomic dysfunction. The mainstay of treatment for established catatonia is benzodiazepines and electroconvulsive therapy (ECT) [ 9 ]. Furthermore, antipsychotics discontinuation—especially first-generation ones—is recommended for the treatment of catatonia [ 10 ].…”
Section: Discussionmentioning
confidence: 99%
“…Catatonia is a potentially life-threatening, motor syndrome, characterized by mental and physical immobilization and stereotypic behaviors, which may alternate with agitation and complicated with rigidity, hyperthermia and autonomic dysfunction. The mainstay of treatment for established catatonia is benzodiazepines and electroconvulsive therapy (ECT) [ 9 ]. Furthermore, antipsychotics discontinuation—especially first-generation ones—is recommended for the treatment of catatonia [ 10 ].…”
Section: Discussionmentioning
confidence: 99%
“…Dopamine dysfunction has also long been postulated as a cause for catatonia symptoms. There is some evidence that the potency of a dopamine D2 receptor blockage is directly related to the risk of exacerbating catatonia or even provoking malignant features [ 36 ]. This can be seen in neuroleptic malignant syndrome, which can manifest as catatonia.…”
Section: Catatonia Causes Presentation and Pathophysiologymentioning
confidence: 99%
“…A 2020 review by prominent ECT critics concludes 'There is no evidence that ECT is effective for … its target diagnostic groupseverely depressed people, or for suicidal people, people who have unsuccessfully tried other treatments first, involuntary patients, or children and adolescents'. 8 Such claims, common within anti-ECT literature, 9,10 seem strange and are easily challenged, given considerable evidence and abundant patient and clinical testimonies to major benefits, 1,3,[11][12][13][14][15] including many calling for ECT's use not to be restricted to 'last-resort' treatment. 1,3,11,12,15 Research on ECT's effectiveness is too extensive to summarise or assess here.…”
Section: Claim 1: Lack Of Evidence For Effectivenessmentioning
confidence: 99%