&lt;p&gt;Menopausal Symptoms and Associated Social and Environmental Factors in Midlife Chinese Women&lt;/p&gt;

Zhang, Lingyan; Ruan, Xiangyan; Cui, Yuanshan; Gu, Muqing; Mueck, Alfred O.

doi:10.2147/cia.s278976

Cited by 26 publications

(14 citation statements)

References 43 publications

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“…Increased negative psychological symptoms (anxiety and depression [ 7 ]) and decreased cognitive performance during menopausal transition could last up to the age of 60 and then get worse during the following years [ 8 ]. The risk of osteoporosis [ 9 ], hypertension [ 10 ], cardiovascular diseases [ 11 ] and metabolic disorders [ 12 ] would increase as well.…”

Section: Introductionmentioning

confidence: 99%

Severity and factors of menopausal symptoms in middle-aged women in Gansu Province of China: a cross-sectional study

et al. 2021

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Objective To investigate the severity and risk factors of menopausal symptoms in the middle-aged women in Gansu Province of China. Methods In this cross-sectional study, a total of 7319 women (aged 40–55 years) attended the health survey in Gansu Province in China were enrolled. Information on demographics, menopausal status, reproductive history, and history of chronic diseases was collected via a structured questionnaire. Severity of menopausal symptom was evaluated by the Modified Kupperman Menopausal Index. Ordinal logistic regression model was applied to explore its risk factors. Results A total of 7319 participants were included in present study, among them, 3606 (49.27%) had moderate or severe menopausal symptom. Compared with premenopausal women, perimenopausal and postmenopausal women have a higher mKMI score. We observed that older age, higher BMI, non-married status, longer duration of menstruation (≥ 7 days), number of pregnancy (> 3 times), longer duration of breastfeeding (> 12 months), peri- or post-menopausal status, and menopause hormone therapy was positively associated with menopausal symptom score, while higher level of family income, educational and physical activity, and history of gynecological, breast or chronic disease were negatively associated with the score. Conclusions Numerous factors were associated with the severity of menopausal symptom among the Chinese women. Because it was gradually increased with aging, more attention is warranted to manage the menopausal symptom.

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Section: Introductionmentioning

confidence: 99%

Severity and factors of menopausal symptoms in middle-aged women in Gansu Province of China: a cross-sectional study

et al. 2021

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“…Коррекция и терапия климактерического синдрома, в особенности его психоэмоциональной составляющей, вне всякого сомнения, являются на сегодняшний день одним из актуальных вопросов, требующих обсуждения и решения [7,13,14]. Не ново для практикующих гинекологов, что решением данной проблемы будет назначение менопаузальной гормональной терапии, о чем четко написано в клинических рекомендациях Минздрава РФ «Менопаузальная гормонотерапия и сохранение здоровья женщин в зрелом возрасте», утвержденных в 2015 г.…”

Section: Introductionunclassified

Psycho-emotional state of women during the perimenopausal transition

Markova

Хашукоева

2023

Medicinskij sovet

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A woman’s health during the perimenopausal transition is not irrelevant because of the risk zone in which this category of women falls. Mature patients often have complaints associated with the menopausal syndrome. The increase in life expectancy of women, their active lifestyle that they want to maintain, which is not always possible due to the presence of a number of adverse factors such as the environment, stress factors, the presence of chronic diseases that tend to frequent exacerbations, all this aggravates the overall condition of women and primarily has a negative impact on their psycho-emotional health. The menopausal syndrome, which can debut during the perimenopausal transition, further complicates the woman’s condition. The job of a specialist gynaecologist is to help and manage these patients. It would seem that there is no question: the clinical guidelines and protocols are clearly prescribed algorithms for the management and therapy of such patients, where it is stated in black and white about the prescription of menopausal hormone therapy, which is pathogenetic and justified in the development of the menopausal syndrome and the complaints associated with it. But the prescription of this therapy is associated with a set of risks and side effects. Non-hormonal therapy is a good alternative in the treatment of menopausal disorders, given that hormonal treatment is contraindicated in a number of women. This article presents a cross-section of the literature data on the results of prescribing a dietary supplement MENSE® (Aquion JSC, Russia) in women with psycho-emotional tension during menopause. MENSE® complex contains an impressive range of components (β-alanine, 5-hydroxytryptophan, phytoestrogens – soy isoflavones, B vitamins, folic acid, vitamins E and C) favorably affecting the female body and improves the quality of her life during perimenopause. This complex can be recommended for patients with menopausal syndrome as an effective therapeutic agent for the period of selection of menopausal hormonal therapy or the presence of contraindications to it. MENSE® is an effective complex for improving the quality of life of perimenopausal women against the background of psycho-emotional conditions.

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“…The extended arrays of symptoms attributed to menopause gradationally deteriorate the well-being of these women and ultimately their quality of life. Thereby, maintaining the optimal health of postmenopausal women with inferior and safe methods is substantial [ 19 , 20 ].…”

Section: Introductionmentioning

confidence: 99%

“…Considering that the pieces of evidence evaluating the efficacy of curcumin and vitamin E in relieving menopausal symptoms are poor and contradictory, it is necessary to conduct an exhaustive randomized clinical trial in this regard [ 9 , 15 , 16 , 20 ].…”

Section: Introductionmentioning

confidence: 99%

Clinical Efficacy of Curcumin and Vitamin E on Inflammatory-Oxidative Stress Biomarkers and Primary Symptoms of Menopause in Healthy Postmenopausal Women: A Triple-Blind Randomized Controlled Trial

Farshbaf‐Khalili

Ostadrahimi

Mirghafourvand

et al. 2022

Journal of Nutrition and Metabolism

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Aims of the Study. Reducing estrogen levels due to menopause activates oxidative and inflammatory processes, which causes symptoms of menopause, anxiety, and sexual dysfunction. As a suggestion, potential anti-inflammatory and antioxidant agents such as curcumin and vitamin E could be used as an effective alternative treatment due to parsimony, suitable access, and fewer side effects. Therefore, the present study was conducted to find out whether supplementation with curcumin and vitamin E affects inflammatory-oxidative stress biomarkers and primary symptoms of menopause in healthy postmenopausal women. Methods Used to Conduct the Study. The present study is a triple-blind parallel randomized controlled trial. Eighty-four eligible postmenopausal women aged 40 to 60 years old were randomly assigned into three groups using block randomization with an allocation ratio of 1 : 1 : 1. The curcumin group received one capsule containing 500 mg curcumin twice a day, the vitamin E group received one 500 mg capsule of vitamin E twice a day, and the placebo group took two placebo capsules containing 500 mg of microcrystalline cellulose (MCC) daily for eight weeks. Demographic and anthropometric characteristics, dietary intake, and early symptoms of menopause were collected at baseline. Serum levels of total antioxidant capacity (TAC), malondialdehyde (MDA), and high sensitivity C-reactive protein (hs-CRP) were measured at baseline and after the intervention. Intervention safety and satisfaction with the intervention were also evaluated. Results of the Study. Eighty-one participants completed the trial and were finally analyzed. There were no statistically significant differences in demographic characteristics and dietary intake of participants (except for vitamin C intake, P = 0.023 ) between the groups at baseline. The mean ± standard deviation (SD) score of total menopause symptoms, depression, anxiety, psychological, vasomotor, and physical domains significantly decreased within all groups ( P < 0.05 ). Between-group analyses indicated that decreasing the mean score of anxiety in the vitamin E group was significantly more than in the placebo group ( P = 0.026 ). The mean (SD) serum levels of MDA and hs-CRP significantly decreased only in the curcumin group ( P = 0.009 and P = 0.025 , respectively). Serum levels of TAC significantly increased in curcumin and vitamin E groups ( P < 0.001 and P = 0.006 , respectively). Conclusions Drawn from the Study and Clinical Implications. Curcumin could improve the oxidative stress (MDA and TAC) and inflammatory (hs-CRP) biomarkers. Vitamin E may also improve the antioxidant status by increasing the TAC levels. The alleviation of anxiety in the vitamin E group was more than in the placebo group. Clinical Trial Registration. The trial was registered at the Iranian Registry of Clinical Trials (https://irct.ir/IRCT20131009014957N6).

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<p>Menopausal Symptoms and Associated Social and Environmental Factors in Midlife Chinese Women</p>

Cited by 26 publications

References 43 publications

Severity and factors of menopausal symptoms in middle-aged women in Gansu Province of China: a cross-sectional study

Severity and factors of menopausal symptoms in middle-aged women in Gansu Province of China: a cross-sectional study

Psycho-emotional state of women during the perimenopausal transition

Clinical Efficacy of Curcumin and Vitamin E on Inflammatory-Oxidative Stress Biomarkers and Primary Symptoms of Menopause in Healthy Postmenopausal Women: A Triple-Blind Randomized Controlled Trial

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