<p>Patient-Reported Outcomes/Satisfaction and Spectacle Independence with Blended or Bilateral Multifocal Intraocular Lenses in Cataract Surgery</p>

Abstract

Purpose: To compare patient-reported outcomes (PROs) and satisfaction results after multifocal intraocular lens (IOL) implantation in three groups: two receiving bilateral implantation of the same IOL and another undergoing blended vision with two different multifocal IOLs. Patients and methods: A questionnaire was administered to patients who had undergone uncomplicated cataract surgery and 2 months of follow-up: the first group underwent bilateral implantation with Alcon's AcrySof ReSTOR 3.0 lens ("3.0/3.0," n=78); the second group underwent implantation with the ReSTOR ActiveFocus 2.5 or the ReSTOR ActiveFocus 2.5 toric lens ("2.5 mini-monovision," n=102); and the third group underwent implantation with the ReSTOR 2.5 lens in the dominant eye and the ReSTOR 3.0 lens in the non-dominant eye ("2.5/3.0," n=89). Results: Overall PROs and satisfaction was similar among the groups. Refractive outcomes and accuracy were similar among the groups, but the 2.5 mini-monovision group reported better intermediate vision. Refractive outcome differences were not meaningful among the groups and were not a differentiating factor in PROs. Substantially fewer patients in the 2.5 mini-monovision group noticed glare and halo compared with the 3.0/3.0 group (P<0.0001, chi-square test). No new safety concerns were reported. Conclusion: The 2.5 mini-monovision results in a higher percentage of patients being satisfied with intermediate vision than bilateral ReSTOR 3.0 or blended vision with ReSTOR 2.5/3.0 implants, but overall PRO differences were not statistically significant.

The PanOptix Trifocal IOL vs the ReSTOR 2.5 Active Focus and ReSTOR 3.0-Add Multifocal Lenses: A Study of Patient Satisfaction, Visual Disturbances, and Uncorrected Visual Performance

“…Our previous work compared PROs, satisfaction rates, and spectacle independence between blended or bilateral multifocal IOLs in patients who underwent cataract surgery (AcrySof IQ ReSTOR +2.5 D and ReSTOR +3.0 D, Alcon, Ft. Worth, Texas). 15 We found that the combination of a ReSTOR +2.5 D and ReSTOR +3.0 D resulted in higher patient satisfaction rates for intermediate vision than bilateral ReSTOR +3.0 D implants, but that overall PRO differences were not statistically significant.…”

“…Comparison was made to two previous cohorts of multifocal IOL patients who had undergone similar surgery and responded to a similar questionnaire in a similar time frame. 15 In that study, the 2.5 mini-monovision cohort received the AcrySof IQ ReSTOR ActiveFocus +2.5 D or AcrySof IQ ReSTOR ActiveFocus +2.5 D add toric implant bilaterally, with the dominant eye targeted for emmetropia and the nondominant eye targeted for −0.5 sphere. The “2.5/3.0” cohort was implanted with the AcrySof IQ ReSTOR ActiveFocus +2.5 D implant in the dominant eye and the AcrySof IQ ReSTOR +3.0 D multifocal lens the nondominant eye.…”

“…To account for the difference in exclusion factors between this study and the previously published study, 15 we examined the raw data to perform a subcohort analysis of overall satisfaction and overall spectacle independence (our primary and secondary endpoints) for the subset of 2.5 mini-monovision and 2.5/3.0 patients who met those same refractive criteria.…”

Clinical Outcome of Lentis Comfort Intraocular Lens Implantation

“…At the present time, there have been marked improvements in achieving uncorrected visual acuity at all distances due to the availability of new trifocal IOL designs. [2][3][4][5][6] With the introduction of new IOL technology, the new IOLs are now able to provide a better enhanced depth of focus as compared to previous multifocal or accommodating IOLs. As a result, this has led to improved visual acuity at all distances, better contrast sensitivity, along with a decrease in both halos and glare symptoms.…”

User Friendliness of a Wearable Visual Behavior Monitor for Cataract and Refractive Surgery

“…As only a part of the light used for image generation is sharp, there is a loss of contrast, which is noticeable. In addition, undesirable optical side effects in the form of so-called halos or glare occur, which impair vision, especially at twilight and at night [5,8]. There is no ideal correction for all distances, but through objective measurement using the Visual Behavior Monitor (VBM) regarding distance measurement, ambient lighting and head posture will potentially determine a much more accurate setting and support the choice of IOL.…”