&lt;p&gt;Preoperative Factors Associated with Remote Postoperative Pain Resolution and Opioid Cessation in a Mixed Surgical Cohort: Post Hoc Analysis of a Perioperative Gabapentin Trial&lt;/p&gt;

Hah, Jennifer M.; Hilmoe, Heather E.; Schmidt, Peter P.; McCue, Rebecca; Trafton, Jodie A.; Clay, Debra; Sharifzadeh, Yasamin; Ruchelli, Gabriela; Hernandez‐Boussard, Tina; Goodman, Stuart B.; Huddleston, James I.; Maloney, William J.; Dirbas, Frederick M.; Shrager, Joseph B.; Costouros, John G.; Curtin, Catherine; Mackey, Sean; Carroll, Ian

doi:10.2147/jpr.s269370

Cited by 12 publications

(19 citation statements)

References 46 publications

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“…In this paper, time refers to the time of outcome assessment, which included: three-month, six-month or twelve-month follow-up visits. We estimated risk ratios (RR) of VS and ART adherence associated with a 5-unit change in scores of depression and anxiety symptoms, as other studies have [69,70]. Since depression and anxiety symptoms were highly correlated in our sample, for each outcome, separate models with the same set of covariates were run for depression or anxiety symptoms as the main predictor.…”

Section: Discussionmentioning

confidence: 99%

“…We performed this rescaling because a 1‐unit change in each score is not clinically meaningful, whereas a 5‐unit change is considered potentially clinically significant, implying that a participant has moved from one level of severity to the next [67,68]. This rescaling method has been used in other studies using continuous measures of depression and anxiety symptoms [69,70].…”

Section: Methodsmentioning

confidence: 99%

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The longitudinal association between depression, anxiety symptoms and HIV outcomes, and the modifying effect of alcohol dependence among ART clients with hazardous alcohol use in Vietnam

et al. 2021

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Introduction Mental health disorders may negatively impact HIV outcomes, such as viral suppression (VS) and antiretroviral (ART) adherence among people with HIV (PWH) with hazardous alcohol use. This study evaluates the longitudinal association between depression, anxiety symptoms, VS and complete ART adherence among ART clients with hazardous alcohol use in Vietnam; and examines alcohol dependence as a modifier in this association. Methods This was a secondary data analysis of a trial for hazardous drinking ART clients in Thai Nguyen, Vietnam. From March 2016 to May 2018, 440 ART clients with an Alcohol Use Disorders Identification Test‐Concise (AUDIT‐C) score ≥4 for men and ≥3 for women were enrolled. Individuals were randomized to either a combined intervention, a brief intervention or a standard of care. Data on sociodemographics, depression, anxiety symptoms, alcohol use, VS and ART adherence were collected at baseline, three, six, and twelve months. Generalized estimating equation models controlling for intervention exposure were used to estimate time‐lagged associations. Risk ratios were estimated using Poisson regression with robust variance estimation. Results The mean age of participants was 40.2. The majority was male (96.8%), had at least some secondary school education (85.0%) and had a history of injection drug use (80.9%). No overall effect of depression and anxiety symptoms on VS was observed. When stratified by time, increased anxiety symptoms at six months were associated with VS at 12 months (adjusted risk ratio (aRR) = 1.09; 95% CI 1.02 to 1.17). An increase in depression or anxiety symptoms was associated with a decreased probability of complete ART adherence (depression symptoms: aRR = 0.95; 95% CI: 0.91 to 0.99; anxiety symptoms: aRR = 0.93; 85% CI: 0.88 to 0.99). The negative effects of anxiety symptoms on ART adherence were stronger among participants with alcohol dependence, compared to those without. Conclusions Depression and anxiety symptoms had no overall effect on VS, although they were associated with a lower probability of complete ART adherence. Interventions focusing on mental healthcare for PWH with hazardous alcohol use are needed, and integration of mental healthcare and alcohol reduction should be implemented in HIV primary care settings.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

The longitudinal association between depression, anxiety symptoms and HIV outcomes, and the modifying effect of alcohol dependence among ART clients with hazardous alcohol use in Vietnam

et al. 2021

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“…It is well known that psychological factors play a role in the perception of postoperative pain [ 21 , 25 , 36 ]. This is the first study demonstrating the influence of preoperative anxiety and depression on postoperative pain at different time points of POD #0 after a bariatric surgery.…”

Section: Discussionmentioning

confidence: 99%

Anxiety and Depression Affect Early Postoperative Pain Dimensions after Bariatric Surgery

Gravani

Matiatou

Nikolaidis

et al. 2020

JCM

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Uncontrolled postoperative pain and prolonged immobilization after bariatric surgery have been associated with increased postoperative complications and prolonged hospitalization. The aim of our study was to evaluate the postoperative pain that follows bariatric surgery and identify any psychological factors that may affect the early postoperative perception of pain. The study included 100 patients with obesity (women, n = 61; age 37.4 ± 9.9 years, mean ± standard deviation; Body Mass Index (BMI) 47.6 ± 6.5 kg/m2) who underwent bariatric surgery. Preoperative anxiety and depression were evaluated by the Hospital Anxiety and Depression Scale (HADS), and the quantitative and qualitative dimension of early postoperative pain were evaluated by the McGill Pain Questionnaire Short Form (MPQ-SF). Furthermore, the postoperative analgesia protocol was recorded for each patient. Pain declined gradually during the first 24 h postoperative. Although preoperative anxiety had no correlation with the overall pain of postoperative Day 0, patients with a higher level of preoperative anxiety had significantly more intense and more unpleasant pain at 1 h post operation. In addition, depression influences both the intensity and unpleasantness of pain at different time points (1 h, 4 h and 24 h postoperative). Preoperative pain correlated with educational level, but not with age, BMI, gender, marital status, smoking and surgery type. In conclusion, preoperative anxiety and depression influence the early postoperative pain after bariatric surgery, and their preoperative identification is of major importance to enhance the implementation of fast-track postoperative protocols to prevent complications and prolonged hospitalization.

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“…Some demographic characteristics are also associated with a higher incidence of mental illness (Hah et al, 2020). Table 1 summarizes the demographic characteristics of the patients.…”

Section: Sample Characteristicsmentioning

confidence: 99%

“…The degree of postoperative pain was greatly affected by the degree of anxiety, and the increase of postoperative pain stimulated the anxiety reaction again, forming a cycle of pain and anxiety. Pain can lead to anxiety, and anxiety can enhance pain (Spivey et al, 2018;Gravani et al, 2020;Hah et al, 2020).…”

Section: Preoperative Anxiety Is An Important Predictor Of Postoperative Painmentioning

confidence: 99%

Preoperative Anxiety and Postoperative Pain in Patients With Laparoscopic Hysterectomy

et al. 2021

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Objective: This study was designed to investigate preoperative anxiety situations and postoperative pain degree in Chinese patients undergoing laparoscopic hysterectomy and to analyze the related factors of preoperative anxiety and the correlation between preoperative anxiety and postoperative pain to provide a reference for effective postoperative analgesia management.Methods: A total of 100 female patients undergoing laparoscopic hysterectomy were enrolled in this study and randomly divided into two groups (n = 50, each). In group A, the patients were treated with dexmedetomidine and sufentanil for postoperative analgesia. In group B, the patients were treated with sufentanil alone for postoperative analgesia. All patients were evaluated with a self-rating anxiety scale (SAS) 1 day before the operation. The patients’ pain was evaluated using the numerical rating scale (NRS) 1 day after the operation, and data were recorded.Results: In these 100 patients, the highest preoperative SAS score was 48, and the average score was 40.99 ± 4.55 points, which is higher than the norm in China. There were significant differences in preoperative SAS scores among patients with different occupations and previous surgical experience (P < 0.05). There was no significant difference in SAS scores among patients with different education levels (P > 0.05). The postoperative NRS score of group A was significantly higher than that of group B, and the difference was statistically significant (P < 0.05). The correlation coefficients between SAS scores and NRS scores in groups A and B were 0.836 and 0.870, respectively, presenting with a significantly positive correlation.Conclusion: Preoperative anxiety is an important predictor of postoperative pain. Patients undergoing laparoscopic hysterectomy have preoperative anxiety. The degree of anxiety is influenced by the occupation and previous operation experience of the patients, and patients with higher preoperative anxiety have greater postoperative pain. In addition, we should not neglect the management of postoperative pain because of the small trauma of laparoscopic surgery, and dexmedetomidine combined with sufentanil can improve the postoperative analgesic effect.

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<p>Preoperative Factors Associated with Remote Postoperative Pain Resolution and Opioid Cessation in a Mixed Surgical Cohort: Post Hoc Analysis of a Perioperative Gabapentin Trial</p>

Cited by 12 publications

References 46 publications

The longitudinal association between depression, anxiety symptoms and HIV outcomes, and the modifying effect of alcohol dependence among ART clients with hazardous alcohol use in Vietnam

The longitudinal association between depression, anxiety symptoms and HIV outcomes, and the modifying effect of alcohol dependence among ART clients with hazardous alcohol use in Vietnam

Anxiety and Depression Affect Early Postoperative Pain Dimensions after Bariatric Surgery

Preoperative Anxiety and Postoperative Pain in Patients With Laparoscopic Hysterectomy

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