&lt;p&gt;Prevalence and Associated Factors of Clinical Vitamin A Deficiency Among Pre-School Children 1–5 Years of Age in Rural Kebeles in Farta District, South Gondar Zone, Ethiopia: A Mixed Methods Study&lt;/p&gt;

Yisak, Hiwot; Elmneh, Rishah; Taklual, Wubet; Ewunetei, Amien; Kefale, Belayneh

doi:10.2147/jmdh.s279571

Cited by 11 publications

(15 citation statements)

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“…Vitamin A deficiency causes squamous metaplasia of the respiratory epithelium, impairment of the airway mucosal barrier, delay of repair, and reduced airway antioxidants 26 . Recent studies have shown that children with vitamin A deficiency are more vulnerable to respiratory tract infection 9 . Vitamin D, on the other hand, plays an essential role in innate immunity.…”

Section: Discussionmentioning

confidence: 99%

“…It has been established that children are more vulnerable to respiratory infections due to their insufficient immunity 8 . Deficiencies of vitamin A and 25‐hydroxy vitamin D (25(OH)D), two essential nutrients for maintaining immunity, have been found to make children susceptible to respiratory infections, including MPP 8‐10 . Although decreased levels of immune‐related factors such as vitamin A and 25(OH)D have been found in many patients with respiratory infections, the correlations between these factors and the disease severity have not been examined.…”

Section: Introductionmentioning

confidence: 99%

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Correlations between Serum P2X7, Vitamin A, 25‐hydroxy Vitamin D, and Mycoplasma Pneumoniae Pneumonia

Meng

Chen

Guo

et al. 2021

Clinical Laboratory Analysis

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Background Identifying new molecular diagnostic markers for Mycoplasma Pneumoniae Pneumonia (MPP) has always been an essential topic since MPP cases have increased every year, especially among children. Here, we examined the correlation between serum level of Purinergic receptor P2X7, vitamin A, and 25‐hydroxy vitamin D (25(OH)D) and the severity of MPP, aiming to identify molecules that have the potential to become diagnostic markers. Methods This study was conducted on 186 cases aged 1–14 (136 MPP and 50 non‐MPP patients). Serum levels of Purinergic receptor P2X7, vitamin A, 25(OH)D, and multiple inflammatory and immune factors were measured, compared, and tested for statistical significance. Results Serum P2X7, tumor necrosis factor‐α (TNF‐α), and interleukin‐1β (IL‐1β) levels were significantly increased in severe MPP patients, while serum vitamin A, 25(OH)D, IgA, and IgG levels were significantly decreased. Conclusion Our results demonstrated a positive correlation between serum P2X7 level and the severity of MPP, and negative correlations between serum levels of vitamin A and 25(OH)D and the severity of MPP, suggesting that high serum levels of P2X7 and low serum levels of vitamin A and 25(OH)D may indicate relatively severer MPP.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Correlations between Serum P2X7, Vitamin A, 25‐hydroxy Vitamin D, and Mycoplasma Pneumoniae Pneumonia

Meng

Chen

Guo

et al. 2021

Clinical Laboratory Analysis

View full text Add to dashboard Cite

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“…Vitamin A deficiency (VAD) is a serious public health problem and one of the nutritional challenges faced by children in low-income countries, especially among those from the poorest communities [1]. Pre-school children are the most vulnerable population group to VAD [2], due to the relatively high demand for vitamin A during this period of rapid growth and development [2]. VAD in this age group is aggravated by low micronutrient intake and high incidence of infections [3,4].…”

Section: Introductionmentioning

confidence: 99%

Residential Food Environment, Household Wealth and Maternal Education Association to Preschoolers’ Consumption of Plant-Based Vitamin A-Rich Foods: The EAT Addis Survey in Addis Ababa

et al. 2022

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Vitamin A deficiency is common among preschoolers in low-income settings and a serious public health concern due to its association to increased morbidity and mortality. The limited consumption of vitamin A-rich food is contributing to the problem. Many factors may influence children’s diet, including residential food environment, household wealth, and maternal education. However, very few studies in low-income settings have examined the relationship of these factors to children’s diet together. This study aimed to assess the importance of residential food availability of three plant-based groups of vitamin A-rich foods, household wealth, and maternal education for preschoolers’ consumption of plant-based vitamin A-rich foods in Addis Ababa. A multistage sampling procedure was used to enroll 5467 households with under-five children and 233 residential food environments with 2568 vendors. Data were analyzed using a multilevel binary logistic regression model. Overall, 36% (95% CI: 34.26, 36.95) of the study children reportedly consumed at least one plant-based vitamin A-rich food group in the 24-h dietary recall period. The odds of consuming any plant-based vitamin A-rich food were significantly higher among children whose mothers had a higher education level (AOR: 2.55; 95% CI: 2.01, 3.25), those living in the highest wealth quintile households (AOR: 2.37; 95% CI: 1.92, 2.93), and in residentials where vitamin A-rich fruits were available (AOR: 1.20; 95% CI: 1.02, 1.41). Further research in residential food environment is necessary to understand the purchasing habits, affordability, and desirability of plant-based vitamin A-rich foods to widen strategic options to improve its consumption among preschoolers in low-income and low-education communities.

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“…And also high prevalence of vitamin A de ciencies among young children in Vietnam (47.3%) (9). In Ethiopia also vitamin A de ciency is a major public health problem because more than one -third (37.7%) of children had de ciency of serum retinol level, and also the prevalence of clinical vitamin A de ciency, Bitot's spot ranges from 0.8-1.46% and night blindness 1.2% (10)(11)(12). Studies in Ethiopia also showed that Consumption of animal source foods among children age 6-23 months were very low (13) and the prevalence of poor consumption of foods rich in vitamin A was high( 62.3%) (14).…”

Section: Introductionmentioning

confidence: 99%

Spatial distribution and Determinates of poor consumption of foods rich in vitamin A among children aged 6–23 months in Ethiopia using data from Ethiopia Demographic and Health Survey 2019: Spatial and Multilevel Analysis

Muhye

Assimamaw

Tamir

et al. 2022

Preprint

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Introduction: Vitamin A is an essential element that supports rapid growth, builds the immune system, and prevents infection. In impoverished countries like Ethiopia, however, consumption of vitamin A-rich foods is a major problem. Thus, this study aimed to investigate the spatial distributions and determinants of poor consumption of foods rich in vitamin A among children aged 6–23 months in Ethiopia. Methods Data were obtained from the Ethiopian Demographic and Health Survey (EDHS) 2019. Spatial autocorrelation was done to test whether the poor consumption of foods rich in vitamin A had spatial dependency or not. Spatial SAT scan analysis and Hotspot (Getis Ord Gi*) were used to detect spatial clustering of poor consumption. A multilevel binary logistic regression model was fitted to identify factors associated with poor consumption of vitamin A-rich foods. An adjusted odds ratio with a 95% confidence interval was calculated, and variables with a p-value less than 0.05 were declared to be significant predictors of poor consumption of vitamin A-rich foods. Result The analysis looked at 1,605 children aged 6 to 23 months. In Ethiopia, poor consumption of vitamin A-rich foods was found to be prevalent in 61.2% of the population, with significant spatial variation. Spatial clustering of poor consumption of foods rich in vitamin A was observed in the Amhara, Somali, and Afar regions. At the individual level, the odds of poor consumption of foods rich in vitamin A among children aged 12–17 and 18–23 months were 0.57 (95%CI (0.39, 0.84)) and 0.39 (95%CI (0.26, 0.58)) respectively. At the community level, the odds of poor consumption of foods rich in vitamin A in Afar, Amhara and Somali were 6.07 (95%CI (2.59, 14.23)), 2.27 (95% CI (1.16, 4.44)) and 57.39 (95%CI (11.76, 279.90)) respectively. Conclusion In Ethiopia, poor consumption of vitamin A-rich foods among children aged 6 to 23 months varied significantly by region, with the highest prevalence found in the Amhara, Somali, and Afar regions. Child age, media exposure, maternal education, and regions were the significant predictors of poor consumption of foods rich in vitamin A. Through improving maternal education and creating awareness through mass media, interventions are targeted to improve the consumption of foods rich in vitamin A.

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<p>Prevalence and Associated Factors of Clinical Vitamin A Deficiency Among Pre-School Children 1–5 Years of Age in Rural Kebeles in Farta District, South Gondar Zone, Ethiopia: A Mixed Methods Study</p>

Cited by 11 publications

References 15 publications

Correlations between Serum P2X7, Vitamin A, 25‐hydroxy Vitamin D, and Mycoplasma Pneumoniae Pneumonia

Correlations between Serum P2X7, Vitamin A, 25‐hydroxy Vitamin D, and Mycoplasma Pneumoniae Pneumonia

Residential Food Environment, Household Wealth and Maternal Education Association to Preschoolers’ Consumption of Plant-Based Vitamin A-Rich Foods: The EAT Addis Survey in Addis Ababa

Spatial distribution and Determinates of poor consumption of foods rich in vitamin A among children aged 6–23 months in Ethiopia using data from Ethiopia Demographic and Health Survey 2019: Spatial and Multilevel Analysis

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