<p>Prognostic Values of LDH and CRP in Cervical Cancer</p>

Abstract

These authors contributed equally to this workPurpose: Cervical cancer is one of the deadliest tumors among women in China. C-reactive protein (CRP), an indicator of inflammation, and lactate dehydrogenase (LDH), an enzyme ubiquitously expressed in cells, both play important roles in tumor growth and metastasis. Patients and Methods: Based on pre-radiotherapy LDH and CRP median levels, we divided patients into four groups: high LDH and CRP group, high LDH group, high CRP group, and low LDH and CRP group. Then, based on pre-/post-radiotherapy LDH and CRP ratios, we divided patients into four groups: high LDH and CRP ratio group, high LDH ratio group, high CRP ratio group, and low LDH and CRP ratio group. Kaplan-Meier (KM) curves were constructed to show overall survival (OS). A multivariate Cox regression model was employed to identify the independent risk factors. Results: High pre-radiotherapy LDH and CRP levels and increased pre-/post-radiotherapy LDH and CRP ratios were correlated with worst OS compared with the other three groups. Conclusion: LDH and CRP were correlated with outcomes in patients with locally advanced cervical cancer.

<p>Diagnosis Value of Combined Detection of Serum SF, CEA and CRP in Non-Small Cell Lung Cancer</p>

“…Many studies have shown that the increase of CRP is positively correlated with the increase of tumor stage. 9,10 The value of the above three factors in the early diagnosis of lung cancer has been studied, 11,12 but the combination of these three factors as a method of early diagnosis of lung cancer has not been reported. The purpose of this study is to evaluate the diagnostic value of SF, CEA and CRP in lung cancer, improve the early diagnosis rate of lung cancer and provide a more diagnostic basis for clinicians.…”

Effect of Psychological Care Combined with Traditional Chinese Medicine on Postoperative Psychological Stress Response in Patients with Advanced Cervical Cancer

“…As an inflammatory factor, CRP reflects the inflammatory condition and the degree of damage in the body. In normal human serum, the level of CRP is low, and when its level is abnormally elevated, it indicates that the patient's condition is worsening [ 18 ]. The results of this study showed that after treatment, the serum CRP levels of patients significantly decreased, indicating that psychological care combined with traditional Chinese medicine in the treatment of postoperative advanced cervical cancer patients can significantly reduce the level of the inflammatory factor CRP and enhance the immunity of the body, which is consistent with the results of our study [ 17 ].…”

“…As an inflammatory factor, CRP reflects the inflammatory condition and the degree of damage in the body. In normal human serum, the level of CRP is low, and when its level is abnormally elevated, it indicates that the patient's condition is worsening [18].…”

Prognostic Factor in Patients with Advanced, Inoperable Thymic Carcinoma: An Application of the Lung Immune Prognostic Index

“…In recent years, the prognostic utility of hematological and biochemical parameters that can be routinely evaluated in daily clinical practice and that potentially re ect tumor in ammation have been validated. Typically, the neutrophil-to-lymphocyte ratio (NLR) and derived NLR (dNLR), comprising leukocyte fractions, are commonly used parameters [5,6] . In cancer patients, these parameters have been reported to act as predictive and/or prognostic biomarkers, indicating tumor in ammatory status re ected by alterations in peripheral blood leukocytes [6] .…”