“…12,13 An additional limitation of this review was the fact that the studies used multiple diagnostic criteria to diagnose the adolescent girls with PCOS, two studies did not specify diagnostic criteria and only one study reported on age of menarche, which is an important factor to determine menstrual irregularity (one of the diagnostic criteria for PCOS). Despite this, most of the studies (n = 6) used commonly accepted criteria, including menstrual irregularity and hyperandrogenism, 24,25,28,29,31,34 and only three studies 26,30,33 used Rotterdam criteria, 6 including pelvic ultrasound, which is no longer recommended for diagnosis of PCOS until 8 years post-menarche. Research including larger sample sizes of better-defined populations, as recently described, is required in adolescent girls with PCOS, but further research in the area of emotional well-being is also required.…”