&lt;p&gt;Review of Testicular Tumor: Diagnostic Approach and Management Outcome in Africa&lt;/p&gt;

Cassell, Ayun; Jalloh, Mohamed; Yunusa, Bashir; Mbodji, Mamadou; Diallo, Abdourahmane; Gaye, O; Labou, Issa; Niang, Lamine; Gueye, Serigne

doi:10.2147/rru.s242398

Cited by 18 publications

(34 citation statements)

References 21 publications

(125 reference statements)

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“…In Africa, the lack of diagnostic tool, poor health seeking behavior and poverty have been a barrier to both diagnosis and treatment of UCs [ 23 ]. Contemporary reviews from Sub-Saharan Africa have revealed much later stages of presentation of other rare genitourinary cancers including penile and testicular tumor [ 24 , 25 ]. To date, the available literature on UC of the upper tract or urethra remains sparse.…”

Section: Discussionmentioning

confidence: 99%

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Diagnostic and Therapeutic Challenges of Rare Urogenital Cancers: Urothelial Carcinoma of the Renal Pelvis, Ureters and Urethra

Cassell¹,

Manobah²,

Willie³

2021

World J Oncol

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Urothelial carcinoma (UC) is a neoplastic growth that affects the lining of the urinary tract from the renal pelvis to the distal urethra. Urothelial cancer occurs less commonly along the upper urinary tract (renal pelvis and ureter) accounting for 5-10% and even rarer along the urethra approximately less than 1%. The incidence of UC of the upper urinary tract and urethra has been reported in the United States and Europe by the Surveillance, Epidemiology, and End Results Program and the Rare Cancers in Europe project, respectively. Considering the rarity of upper tract urothelial carcinoma (UTUC) and primary urethral cancer (PUC), there is a paucity of data from Sub-Saharan Africa. Both the European Association of Urology guideline and the National Comprehensive Cancer Network guideline have provided some clinical updates on the management of UTUC and PUC. However, UTUC and PUC present mostly at a more advanced stage than UC of bladder. A high index of suspicion is necessary for diagnosis even more for UTUC. Organ-sparing surgery is possible for both localized UTUC and PUC but stringent follow-up with urine cytology, endoscopy and imaging is mandated for early detection of recurrence.

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Section: Discussionmentioning

confidence: 99%

“…World J Oncol. 2021;12(1): [20][21][22][23][24][25][26][27] and excision of the bladder cuff because of a considerable risk of tumor recurrence in this area. There is strong evidence to suggest that adjuvant instillation of mitomycin within 72 h of surgery can reduce the recurrence rate within the first year [2,9,10].…”

Section: Rare Urogenital Cancersmentioning

confidence: 99%

Diagnostic and Therapeutic Challenges of Rare Urogenital Cancers: Urothelial Carcinoma of the Renal Pelvis, Ureters and Urethra

Cassell¹,

Manobah²,

Willie³

2021

World J Oncol

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“…As in other non-seminomatous tumors, the treatment of embryonal carcinoma is based primarily on the chemotherapy [6] but typical treatment for a suspicious testicle mass is orchiectomy. Considering that embryonal carcinoma is resistant to radiation, treatment protocol consists of orchiectomy and chemotherapy [5,9]. Our patient received surgical treatment with left high radical orchiectomy and chemotherapy.…”

Section: Discussionmentioning

confidence: 99%

“…For this reason, early diagnosis and treatment of embryonal carcinoma cases are very important [3]. As in many testicular tumors, embryonal carcinoma is also detected by the patient or coincidentally in examination in form of pain-free or (less frequently) painful palpable mass [5][6][7][8][9][10]. When pain or mass is detected in testis, the first imaging method to be used is USG.…”

Section: Introductionmentioning

confidence: 99%

Pure embryonal carcinoma of the testis in an adult male patient: case report

Sirin¹,

Goker²,

Mızrak³

et al. 2021

SPEMM

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As a case presentation, the present paper aims to present a patient with pure embryonal carcinoma, which is rarely seen, together with the relevant literature. Th e case is a 36-year-old male patient, who applied to the clinic with complaints of pain and swelling in the left testis. In the scrotal doppler ultrasonography, hypoechoic solid lesion contoured to the lobule almost fi lling the left testis and having the size of 25x60 mm were observed. Histopathological and immunohistochemical analysis of the this case was diagnosed with pure embryonal carcinoma. All the patients with complaint of pain-free mass in testis should be investigated. Although the pure embryonal carcinoma is rarely seen, it is one of the tumors that can be clinically and histopathologically confused with other testis tumors and should be considered for the patients applying to the clinic with complaints of pain-free mass in testis.

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confidence: 99%

Giant Testicular Cancer: Clinical Picture

Mohammed¹,

ZOJ²,

Jaafar³

et al. 2021

austinjurol

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Testicular tumour is the most malignant cancer in young males 15 to 34 years of age. Its accounts for 1% of all male cancer and 5% of urological malignancy [1]. The management of this type of cancer is radical inguinal orchiectomy which is the gold standard for the diagnosis and initial management of a suspected testicular cancer. Trans -scrotal orchiectomy is discouraged because scrotal violation is associated with higher rates of local recurrence and altered pathways of metastatic dissemination [2]. We report a young patient 23 years old. History: Chronic smoking, cannabis. Admitted for large bursa evolving for 14 months. The history of the disease dates back to 14 months by the gradual increase in the volume of the bursa with an alteration of the general status with a weight loss estimated at 10kgs. Clinical examination showed: right hemi-scrotum increased in volume with a hard consistency with a left testicle repressed in extreme lateral and some inflammatory lesions. Right testis was not palpable with a cord repulsed and glued to the inguinal orifice. The ultrasound of the scrotal content showed: large right testis hypervascularized with moderate anterior cloisonnae hydrocele, bilateral testicular microlithiasis. Tumor markers: Lactate Dehydrogenase (LDH) 229IU, beta-Human Chorionic Gonadotropin (beta-hCG) 29.73mUI/ ml, Alpha-Foetoprotein (AFP) 400IU/ml. Patient benefited from a complete pre-operative assessment that did not object to any abnormality. Programmed for a right inguinal orchiectomy and reduction scrotoplasty (Figure 1).

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<p>Review of Testicular Tumor: Diagnostic Approach and Management Outcome in Africa</p>

Cited by 18 publications

References 21 publications

Diagnostic and Therapeutic Challenges of Rare Urogenital Cancers: Urothelial Carcinoma of the Renal Pelvis, Ureters and Urethra

Diagnostic and Therapeutic Challenges of Rare Urogenital Cancers: Urothelial Carcinoma of the Renal Pelvis, Ureters and Urethra

Pure embryonal carcinoma of the testis in an adult male patient: case report

Giant Testicular Cancer: Clinical Picture

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