<p>The Association Between Caustic Ingestion and Psychiatric Comorbidity Based on 396 Adults Within 20 Years</p>

Abstract

High prevalence of psychiatric comorbidities (PCs) has been widely documented in caustic substance ingestion cases. However, their effect on the clinical features and prognostic outcomes remains unclear due to the paucity of discussion. We report on detailed clinical courses with long-term multifaceted outcomes and review the association between caustic ingestion and each specific PC. Patients and Methods: The retrospective chart review included 396 adults (median follow-up, 16.6 months) with and 377 without (control group) PCs treated between 1999 and 2018 at Chang Gung Memorial Hospital. All PCs were diagnosed/confirmed by psychiatrists through face-to-face interviews. Results: The PCs predicted serious esophagogastroduodenoscopy grading, higher rates of admission/surgery/intensive care unit stay, increments of systemic/gastrointestinal complications, and poorer 5-year overall survival rates. The poor survival among patients with PCs was highly consistent with their baseline characteristics. Significantly advanced age, more non-PCs, alcoholism, illicit drug abuse, and baseline unhealthy status resulted in statistically higher risks of severe complications and limited recovery. Conclusion: PCs changed clinical patterns and had critical roles in the survival outcomes of caustic injury victims. Clinical awareness achieves benefit by limiting injuries in mild cases or allowing emergent interventions in severe cases. Future studies based on worldwide populations are essential for realizing geographic differences.

Chemical Burn-Induced Corrosive Epiglottitis in an Elderly Patient with Major Depression

“…A national population-based study has indicated that patients with psychiatric disorders are more likely to have GI corrosive injury than persons without mental illness [ 6 ]. In addition, previous studies have reported that patients with psychiatric disorders have a worse prognosis after accidentally ingesting corrosive substances compared with people without mental illness, which may be related to the higher intake amount [ 7 ]. However, some articles had a different point of view and suggested that patients with a history of psychopathology might have a better outcome of corrosive esophageal injury because caregivers are more likely to be on the lookout for warning signs in these patients, and act promptly by bringing them to medical attention.…”

Endoscopic Aspects of Caustic Injuries of the Upper Gastrointestinal Tract in Parakou, Benin Republic: A Multicenter Study

“…According to a study based on 396 adults, Chen et al [14] in Taiwan reported that the presence of psychiatric comorbidities predicted severe endoscopic lesions of the upper GI tract, higher rates of surgical admission and intensive care unit stay, an increase in systemic and gastrointestinal complications and poorer 5-year relative survival rates in patients with caustic ingestion.…”

Validity and Reliability of the European Organization Research and Treatment of Cancer Quality of Life Questionnaire-Oesophagogastric 25 in Indian Patients With Corrosive-Induced Benign Refractory Esophageal Strictures

“…The event of corrosive ingestion itself is highly stressful and often performed as a suicidal act in adults [ 8 ]. During the chronic phase, individuals with refractory strictures suffer from dysphagia, aspiration, malnutrition, social isolation, multiple hospital visits, and a poor quality of life [ 3 , 16 , 17 ]. Thus, there is a need to gather patient-reported outcomes to help clinicians decide whether repeated endoscopic dilation of corrosive-induced esophageal strictures is appropriate and beneficial to patients.…”