2020
DOI: 10.2147/cia.s252432
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<p>The Changes in Medication Prescribing Among the Older People with Cognitive Impairment in the Acute Care Setting</p>

Abstract: Purpose: Most older people with cognitive impairment usually have multiple comorbidities. In the last decade, the guidelines for the management of chronic diseases have been changed, leading to changes in the patterns of medication prescribing and in the prevalence of drugrelated problems (DRPs). The main objectives were to explore the changes in medication use and in the prevalence of polypharmacy (PP), the use of potentially inappropriate medications (PIMs) and drug-drug interactions (DDIs) among older hospi… Show more

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“…The number of people living with dementia is increasing worldwide ( Afzal et al, 2014 ). The increasing incidence rates of cognitive impairment and dementia will lead to an increased incidence of various geriatric diseases, which will greatly increase medical investment and impose a heavy socioeconomic burden ( Mangialasche et al, 2009 ; Ruangritchankul et al, 2020 ). There is now evidence that cognitive impairment is related to human inflammation ( Ferrucci and Fabbri, 2018 ; Irwin and Vitiello, 2019 ; Barter et al, 2021 ; Minhas et al, 2021 ).…”
Section: Introductionmentioning
confidence: 99%
“…The number of people living with dementia is increasing worldwide ( Afzal et al, 2014 ). The increasing incidence rates of cognitive impairment and dementia will lead to an increased incidence of various geriatric diseases, which will greatly increase medical investment and impose a heavy socioeconomic burden ( Mangialasche et al, 2009 ; Ruangritchankul et al, 2020 ). There is now evidence that cognitive impairment is related to human inflammation ( Ferrucci and Fabbri, 2018 ; Irwin and Vitiello, 2019 ; Barter et al, 2021 ; Minhas et al, 2021 ).…”
Section: Introductionmentioning
confidence: 99%
“…For example, in the United States, more than 6 million people over the age of 65 had been diagnosed with cognitive dysfunction by 2020, and that number is expected to increase to 13.85 million by 2060 [ 3 ]. The increase of cognitive impairment will lead to an increase in the incidence of various geriatric diseases, which will increase the investment of medical resources and cause a heavy socioeconomic burden [ 4 , 5 ]. Therefore, more effective prevention and control measures are urgently needed.…”
Section: Introductionmentioning
confidence: 99%
“…Moreover, the presence of preoperative cognitive impairment is associated with a substantial increase in the risk of postoperative delirium, postoperative complications, 30-day readmission, discharge to assisted care, and 1-year mortality ( 15 ). Considering the aging population, cognitive impairment has emerged as a significant global public health concern ( 16 ). Therefore, there is an urgent clinical need to identify diagnostic biomarkers that can identify older adults who are susceptible to cognitive impairment.…”
Section: Introductionmentioning
confidence: 99%