2020
DOI: 10.2147/cia.s249196
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<p>The Effect of Mindfulness-Based Stress Reduction (MBSR) on Depression, Cognition, and Immunity in Mild Cognitive Impairment: A Pilot Feasibility Study</p>

Abstract: Background: Mindfulness-based programs have shown a promising effect on several health factors associated with increased risk of dementia and the conversion from mild cognitive impairment (MCI) to dementia such as depression, stress, cognitive decline, immune system and brain structural and functional changes. Studies on mindfulness in MCI subjects are sparse and frequently lack control intervention groups. Objective: To determine the feasibility and the effect of mindfulness-based stress reduction (MBSR) prac… Show more

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Cited by 39 publications
(41 citation statements)
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References 122 publications
(173 reference statements)
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“…Essa abordagem foi acompanhada por 2 meses, com duração de 2 horas e meia. As avaliações foram realizadas no pré e pós-tratamento, estendendo-se até 6 meses, para observar a eficácia do tratamento 16 .…”
Section: Resultsunclassified
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“…Essa abordagem foi acompanhada por 2 meses, com duração de 2 horas e meia. As avaliações foram realizadas no pré e pós-tratamento, estendendo-se até 6 meses, para observar a eficácia do tratamento 16 .…”
Section: Resultsunclassified
“…O grupo supostamente demonstrou melhor velocidade psicomotora, o que não foi observado na fase de acompanhamento27. Em relação ao perfil imunológico, ambos os grupos demostraram melhorias, mas os resultados foram mais evidentes no grupo MBSR 16 .…”
Section: Resultsunclassified
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“…Compared with the control, in the periphery, higher levels of soluble TNF receptor2 (sTNFR2), IL-6, monocyte chemoattractant protein-1 (MCP-1) were identified in MCI, and levels of high-sensitivity CRP (hs-CRP), IL-6, sTNFR1, sTNFR2, IL-1β increased in AD. In patients diagnosed with MCI, 8 weeks of MBSR in comparison to cognitive training significantly reduced the activation of some subsets of monocytes, which were central detectors and modulators of inflammation ( n = 20) [ 56 ]. Among older adults with mild cognitive impairment, mindful awareness practice (MAP) exhibited significant reductions in hs-CRP after 9 months for all participants in the MAP group and in IL-6 and IL-β at 3 months for males of MAP, compared to the health education program group ( n = 55) [ 57 ].…”
Section: Potential Effects Of Mbi On the Immune Systemmentioning
confidence: 99%
“…Among older adults with mild cognitive impairment, mindful awareness practice (MAP) exhibited significant reductions in hs-CRP after 9 months for all participants in the MAP group and in IL-6 and IL-β at 3 months for males of MAP, compared to the health education program group ( n = 55) [ 57 ]. The level of TNF-α was not changed by both MBSR [ 56 ] and tai chi [ 58 ]. Another detrimental neurodegenerative disorder, Parkinson’s disease (PD), also exhibits higher peripheral concentrations of inflammatory markers—including IL-6, TNF, IL-1β, IL-2, IL-10, CRP and regulated upon activation, normal T cell expressed and presumably secreted (RANTES)—according to a meta-analysis that included 25 studies [ 80 ].…”
Section: Potential Effects Of Mbi On the Immune Systemmentioning
confidence: 99%