<p>The Prevalence of Detrusor Underactivity and its Symptoms Co-relation with Urodynamic Study Findings in Patients with Lower Urinary Tract Symptoms</p>

Abstract

This study determines the prevalence and clinical presentation of detrusor underactivity (DU) and its urodynamic characteristics in adult patients with lower urinary tract symptoms (LUTS). Patients and Methods: This retrospective study has reviewed the symptoms and urodynamic study (UDS) findings of 283 patients with LUTS. Chi-square analysis was used to present the prevalence of UDS characteristics in both sexes. Results: Out of records of 206 patients included in this study, fifty-one (24.76%) patients were diagnosed with DU based on bladder contractility index. Storage lower urinary tract symptoms were the most prevalent characteristic presentation in both sexes as compared to the difficulty in voiding, recurrent urine retention, and urinary incontinence. Bladder outlet, sphincter EMG findings, and degree of DU were significantly correlated with gender. Conclusion: DU is a prevalent and sophisticated bladder pathology rather than a simple one. It requires more attention from the urologists, and evaluations, including UDS, to differentiate it from other pathologies.

Changes in transient receptor potential vanilloid 1 and transient receptor potential vanilloid 4 in patients with lower urinary tract dysfunction

“…Additionally, there are several downsides to UDS that should be considered before interpretation [ 19 ]. Also, there are no standard, detailed urodynamic definitions or diagnostic criteria for DU related to complex bladder pathophysiology [ 20 ]. This issue was a limitation of our study and a limitation of UDS in the diagnosis of LUTD.…”

Underactive urinary bladder – Masquerading as abdominal ascites

“…[ 5 ] This is more prevalent among institutionalized elderly patients. [ 6 ] Jeong et al . [ 7 ] showed that detrusor underactivity often coexists with other lower urinary tract dysfunctions.…”

Recent insights into pharmaceutical treatments for underactive bladder: a scoping review of recent studies

“…Evaluations for non-neurogenic LUTS detected UAB in up to 28% of males aged under the age of 50 years, and 48% of those over the age of 70 years. 6 Similarly, UAB was detected in up to 45% of females aged over 70 years. 6 Furthermore, DU has been attributed to both myogenic and neurogenic aetiologies and may no longer be exclusively associated with the aging population.…”

“…6 Similarly, UAB was detected in up to 45% of females aged over 70 years. 6 Furthermore, DU has been attributed to both myogenic and neurogenic aetiologies and may no longer be exclusively associated with the aging population. 7 The absence of DU pathogenesis research corresponds to current ineffective treatment options for UAB.…”