&lt;p&gt;Top-down fabrication-based nano/microparticles for molecular imaging and drug delivery&lt;/p&gt;

Aryal, Susmita; Park, Hyungkyu; Leary, James F.; Key, Joe L.

doi:10.2147/ijn.s212037

Cited by 48 publications

(20 citation statements)

References 55 publications

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“…With the help of top-down nanofabrication techniques such as lithography, monodispersed particles with controlled shapes and dimensions can be generated. The top-down approach used to synthesize nanoparticles proves to be an alternative to overcome the disadvantages and obstacles of the bottom-up method [98,99]. The approaches described above have multiple advantages and disadvantages; however, comparing the two techniques has shown that the bottom-up method is cost-effective and facilitates the manufacturing of 2D and 3D materials with multiple applications [78].…”

Section: Synthesis Of Magnetite-silica Core/shell Structuresmentioning

confidence: 99%

Magnetite-Silica Core/Shell Nanostructures: From Surface Functionalization towards Biomedical Applications—A Review

et al. 2021

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The interconnection of nanotechnology and medicine could lead to improved materials, offering a better quality of life and new opportunities for biomedical applications, moving from research to clinical applications. Magnetite nanoparticles are interesting magnetic nanomaterials because of the property-depending methods chosen for their synthesis. Magnetite nanoparticles can be coated with various materials, resulting in “core/shell” magnetic structures with tunable properties. To synthesize promising materials with promising implications for biomedical applications, the researchers functionalized magnetite nanoparticles with silica and, thanks to the presence of silanol groups, the functionality, biocompatibility, and hydrophilicity were improved. This review highlights the most important synthesis methods for silica-coated with magnetite nanoparticles. From the presented methods, the most used was the Stöber method; there are also other syntheses presented in the review, such as co-precipitation, sol-gel, thermal decomposition, and the hydrothermal method. The second part of the review presents the main applications of magnetite-silica core/shell nanostructures. Magnetite-silica core/shell nanostructures have promising biomedical applications in magnetic resonance imaging (MRI) as a contrast agent, hyperthermia, drug delivery systems, and selective cancer therapy but also in developing magnetic micro devices.

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Section: Synthesis Of Magnetite-silica Core/shell Structuresmentioning

confidence: 99%

Magnetite-Silica Core/Shell Nanostructures: From Surface Functionalization towards Biomedical Applications—A Review

et al. 2021

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“…crushing, grinding or etching out crystals). A top-down method can thus be considered as an approach where the building blocks are removed from the substrate to form the particles (Aryal et al, 2019).…”

Section: Types Of Structured Particles and Methods Of Their Synthesismentioning

confidence: 99%

Numerical Modelling of Formation of Highly Ordered Structured Micro- and Nanoparticles – A Review

Gac

2022

KONA

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The aerosol particles play a significant role in the environment and human health. They are also increasingly used in medicine (drug carriers), preparation (nanocatalysts) and many other fields. For these applications, the particles have to possess unique properties which arise directly from their structure and topology. Indeed, the functionality of the nanostructure particle is defined through its application, like chromatography, sensors, microelectronics, catalysis, and others. That is the reason why people are more and more interested in manufacturing structured particles. The structured particles are the particles with well-defined topological structure. Examples of such particles are porous particles, hollow particles (with the empty space inside), or multi-component particles with the segregation of components in the particle structure. Such particles usually have very interesting features, e.g. porous particles have a significantly larger surface area than the simple spherical particles with similar volume. The present paper contains a comprehensive review of the numerical simulation methods of the formation of highly ordered structured particles. The most important methods will be described in detail and their fields of application (with specific examples), advantages, limitations and information about their accuracy will be given.

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“…Due to the aforementioned reasons, the toxico-kinetics of engineered nanomaterials are presently under numerous studies (de Jong et al, 2017, [ 186 ]). Due to the fact that the engineered nanomaterials are smaller than 100 nm, these materials could smoothly penetrate cells (Aryal et al, 2019, [ 187 ]). Even though the harmfulness of nanoparticles varies based on their properties (chemical composition, surface energy, charge, shaper, size, and others), they also depend on the living organisms and their diverse DNA covering ratios (Sukhanova et al, 2018, [ 188 ]).…”

Section: Nanomaterials In Textile Industries—environmental Healthmentioning

confidence: 99%

Sustainable Use of Nanomaterials in Textiles and Their Environmental Impact

2020

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At present, nanotechnology is a priority in research in several nations due to its massive capability and financial impact. However, due to the uncertainties and abnormalities in shape, size, and chemical compositions, the existence of certain nanomaterials may lead to dangerous effects on the human health and environment. The present review includes the different advanced applications of nanomaterials in textiles industries, as well as their associated environmental and health risks. The four main textile industry fields using nanomaterials, nanofinishing, nanocoatings, nanofibers, and nanocomposites, are analyzed. Different functional textiles with nanomaterials are also briefly reviewed. Most textile materials are in direct and prolonged contact with our skin. Hence, the influence of carcinogenic and toxic substances that are available in textiles must be comprehensively examined. Proper recognition of the conceivable benefits and accidental hazards of nanomaterials to our surroundings is significant for pursuing its development in the forthcoming years. The conclusions of the current paper are anticipated to increase awareness on the possible influence of nanomaterial-containing textile wastes and the significance of better regulations in regards to the ultimate disposal of these wastes.

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<p>Top-down fabrication-based nano/microparticles for molecular imaging and drug delivery</p>

Cited by 48 publications

References 55 publications

Magnetite-Silica Core/Shell Nanostructures: From Surface Functionalization towards Biomedical Applications—A Review

Magnetite-Silica Core/Shell Nanostructures: From Surface Functionalization towards Biomedical Applications—A Review

Numerical Modelling of Formation of Highly Ordered Structured Micro- and Nanoparticles – A Review

Sustainable Use of Nanomaterials in Textiles and Their Environmental Impact

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