&lt;title&gt;Characterization of stroke lesions using a histogram-based data analysis including diffusion- and perfusion-weighted imaging&lt;/title&gt;

Grzesik, Alexander; Bernarding, Johannes; Braun, J.; Koennecke, Hans–Christian; Wolf, K.-J.; Tolxdorff, Thomas

doi:10.1117/12.383408

Cited by 2 publications

(3 citation statements)

References 7 publications

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“…Bolus track PWI was performed with 5 slices, SL = 7 mm, TE = 56 msec, time resolution 1 second, covering the extended periventricular and callosal lesions. Regional cerebral blood volume (rCBV) and mean transit time (MTT) were calculated using a non‐linear fit of a gamma‐variate with an additive linear component to the transient signal after administration of 20 mL Gadolinium, according to Rosen, et al and Grzesik, et al (13, 14). EPI images were registered using the software tool AIR to reduce intra‐measurement motions (15)…”

Section: Methodsmentioning

confidence: 99%

“…Segmented tissue was color‐encoded and overlaid on the original parameter images to control segmentation results. The technique is illustrated in more detail in Bernarding, et al and Grzesik, et al (11, 14). SE images served for diagnosis of blood brain barrier changes or parenchyma defects (T1w) and to differentiate EPI image distortions from pathologic regions (T2w)…”

Section: Methodsmentioning

confidence: 99%

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Diffusion‐ and perfusion‐weighted MR imaging in a patient with acute demyelinating encephalomyelitis (ADEM)

Bernarding

Braun

Koennecke

2002

Magnetic Resonance Imaging

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To monitor changes of brain tissue metabolism in acute demyelinating encephalitis (ADEM), we examined a patient with suspected ADEM by serial MRI including diffusionand perfusion-weighted imaging (DWI, PWI). Within the inflammatory tissue, the apparent diffusion coefficients were reduced, normal, and increased. Perfusion varied between reduced and normal values, except for small hyperperfused regions. Combining standard MRI with DWI and PWI may elucidate different overlapping phases in cerebral inflammation.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Diffusion‐ and perfusion‐weighted MR imaging in a patient with acute demyelinating encephalomyelitis (ADEM)

Bernarding

Braun

Koennecke

2002

Magnetic Resonance Imaging

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“…More specifically, the exploration of higher dimensional histograms for discriminating tissue in ischemic stroke diagnosis was described by Grzesik et al [29]. They incorporate MR perfusion data and diffusion-weighted MR data in order to integrate the information from both imaging data.…”

Section: Combining Analysis and Visual Explorationmentioning

confidence: 99%

Survey of the Visual Exploration and Analysis of Perfusion Data

Preim

Oeltze

Mlejnek

et al. 2009

IEEE Trans. Visual. Comput. Graphics

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Abstract-Dynamic contrast-enhanced image data (perfusion data) are used to characterize regional tissue perfusion. Perfusion data consist of a sequence of images, acquired after a contrast agent bolus is applied. Perfusion data are used for diagnostic purposes in oncology, ischemic stroke assessment, or myocardial ischemia. The diagnostic evaluation of perfusion data is challenging, since the data are complex and exhibit various artifacts, e.g., motion artifacts. We provide an overview on existing methods to analyze and visualize CT and MR perfusion data. The integrated visualization of several 2D parameter maps, the 3D visualization of parameter volumes, and exploration techniques are discussed. An essential aspect in the diagnosis of perfusion data is the correlation between perfusion data and derived time-intensity curves as well as with other image data, in particular with high-resolution morphologic image data. We discuss visualization support with respect to the three major application areas: ischemic stroke diagnosis, breast tumor diagnosis, and the diagnosis of coronary heart disease.

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<title>Characterization of stroke lesions using a histogram-based data analysis including diffusion- and perfusion-weighted imaging</title>

Cited by 2 publications

References 7 publications

Diffusion‐ and perfusion‐weighted MR imaging in a patient with acute demyelinating encephalomyelitis (ADEM)

Diffusion‐ and perfusion‐weighted MR imaging in a patient with acute demyelinating encephalomyelitis (ADEM)

Survey of the Visual Exploration and Analysis of Perfusion Data

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