The optical fiber has been extensively used as a sensor in some special fields. Because the optical fiber exists crackles itself and also produce the micro-crack as well as local damage, the fatigue behavior of the optical fiber become the main problem we care about. This paper presents the experimental study on the fatigue performance of bare fiber under static, dynamic and cyclic load. The corresponding fatigue life index (Stress corrosion index) n can be obtained, which are 17.14, 11.83 and 5.88, respectively. The experiment data reveal that fatigue life index is related to loading mode and is treated as the indicator of crack propagation resistance of materials. Because dynamic and cyclic loads can induce additional damage, the fatigue life declines dramatically under the same stress levels.