The environment measured surrounding the complex Midcourse Space Experiment spacecraft during its rst week on orbit is reported. A suite of instruments including a pressure sensor, a neutral and an ion mass spectrometer, quartz crystal microbalances, and ashlamp-based water and particle detectors were activated within hours after launch. These instruments measured the gaseous composition, particulate, and lm accretion temporal histories. Spacecraft environment cleanliness and response to operational activities were used to guide decisions about sensor operation. As a result of careful material selection and ground preparation procedures, the measured levels of condensible species were suf ciently low to permit safe sensor operation after only a few days in orbit.