&lt;title&gt;Interferometric sensors based on surface plasmon resonance&lt;/title&gt;

Wu, Chien‐Ming; Joe, Shen-Fen; Chang, Liann‐Be

doi:10.1117/12.463797

Cited by 1 publication

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“…Wu [64,65] of Tsinghua University, studied heterodyne interferometric system and further improved the sensor sensitivity and antijamming capability. The refractive index change of 2 × 10 -7 RIU could be detected in the experiment.…”

Section: The Development Of Spr Sensor and Spr Commercial Instrumentsmentioning

confidence: 99%

Development and Application of Time-Resolved Surface Plasmon Resonance Spectrometer

Mao¹,

Bao²,

Wang³

et al. 2011

AJAC

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Surface plasmon resonance (SPR) sensor, an optical sensor exploiting special electromagnetic waves-surface plasmon polaritons to probe interactions between an analyte in solution and a molecular recognition element immobilized on the SPR sensor surface, has been widely used in various realms, such as investigating biomolecular interactions and binding properties, detection of biological and chemical analytes, environmental monitoring, food safety and medical diagnostics. This paper reviews the development of SPR sensors and SPR commercial instruments, and emphatically introduces the time-resolved surface plasmon resonance (TR-SPR) techniques. The excellent performances of high sensitivity and rapid detection are easily achieved with TR-SPR spectrometer, whereas the traditional SPR spectrometer cannot be accomplished. Therefore, TR-SPR spectrometer is appropriate for real time analysis of bio-recognition events and small molecular dynamics. However, only two commercial TR-SPR instruments have been exhibited at present, Thermo FT-SPR 100 and Autolab ESPRIT (SPRINGLE). Unfortunately, the high-priced instruments are not suitable for extensive applications in laboratories at present. Herein, a novel commercial TR-SPR spectrometer has been introduced in this review.

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Section: The Development Of Spr Sensor and Spr Commercial Instrumentsmentioning

confidence: 99%