In this letter, we propose a novel track-to-track association (TTTA) algorithm based upon the reference topology (RET) feature, which is insensitive to sensor biases. A rigorous mathematical definition of RET is presented. The insensitivity of RET to sensor biases is analyzed theoretically. In order to construct the association cost matrix, we make use of the optimal subpattern assignment (OSPA) metric to measure the distance between two RETs. Simulation results demonstrate the advantages of the proposed algorithm.Index Terms-Multitarget-multisensor tracking, optimal subpattern assignment (OSPA) metric, reference topology (RET), track-to-track association (TTTA).