Photon correlation spectroscopy (PCS) has become a powerful light‐scattering technique for studying the properties of suspensions and solutions of colloids, macromolecules and polymers, that is absolute, non‐invasive and non‐destructive. This text explains the principles of the technique and describes the required instrumentation. It also discusses new developments in instrumentation, which may substantially impact on future applications of this technique. Proper sample preparation is of major importance for the accuracy and precision of the mean size and size distribution results and thus one section is dedicated to sample handling.