The method for Doppler diagnostics of laser evaporation of biological tissues based on autodyne detection (reception on the laser resonator) of backscattered radiation has been developed. In this method, a laser is simultaneously used both as a source of the destructive action of radiation on biotissues and as a sensor of the backscattered diagnostic signal. This review study discusses the possibilities of Doppler diagnostics in relation to the problems of investigating the processes of laser evaporation of biological tissues in real time and laser surgery. This approach can be used to create an optical-information feedback channel in automated and robotic surgical systems based on pulse-periodic pumped single-mode CO2 lasers. Laser surgical systems with such operational feedback can be used in the development of new approaches to precision low-traumatic and organ-save laser operations.