Lumbar chordoma mimicking a neurogenic tumour

Khong, Peter; Milross, John; Cherukuri, Ravi K.

doi:10.1016/j.jocn.2010.07.098

Cited by 7 publications

(4 citation statements)

References 15 publications

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“…Chordoma is considered to be the tumor, which is derived from notochordal remnants. [ 2 , 3 , 5 , 7 , 9 , 14 , 19 , 23 ] The incidence of chordomas is 5/10,000,000, which are rare, low-grade tumors. [ 3 , 5 , 8 ] Comparing with women, chordoma is far more commonly seen in men.…”

Section: Discussionmentioning

confidence: 99%

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A giant lumbar chordoma

Zhou

Hu²,

Wu³

et al. 2018

Medicine

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Rationale:Chordomas are malignant neoplasms derived from incomplete regression of notochordal tissue along the craniococcygeal axis.It is rare for Chordoma arising from the lumbar spine and the traditional long-term prognosis is typically poor.Patient concerns:The persistent pain in the left side of the waist about 2 years.Diagnoses:Chordoma.Interventions:The patient was treated with surgical resection of the total tumor, followed by the spinal internal fixation of L1 to L2 with pedicle screws.Outcomes:After 5 month follow-up,we find the recurrence in the original lesion.At the 15 month follow-up,the patient was dead after a lot of times revisit by various doctor.Lessons:So It is suggest that the diagnosis should be carried out accurately at the early stage, the lesions and source of lesions should be cut away as broadly as possible, also the radiation and chemotherapy should be carried out after the operation as necessary.

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Section: Discussionmentioning

confidence: 99%

“…[ 3 , 5 , 8 ] Comparing with women, chordoma is far more commonly seen in men. [ 5 , 8 , 23 , 24 ] Chordoma is the most common primary malignant bone tumor throughout the spine, as is the sacrum. [ 5 ] In the vertebral chordomas, the lumbar spine was about 40%, and the cervical spine was most common (nearly 50%).…”

Section: Discussionmentioning

confidence: 99%

A giant lumbar chordoma

Zhou

Hu²,

Wu³

et al. 2018

Medicine

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“…Since other tumors especially metastatic lesions are much more frequent, these are often favored and surgical resection is planned accordingly. There are many published cases of chordomas where other diagnoses were presumed preoperatively [9][10][11][12][13], and at least one case report where preoperative biopsy was not done and an intraoperative diagnosis of chordoma was made, changing the operative plan to en bloc resection [9].…”

Section: Discussionmentioning

confidence: 99%

The importance of preoperative tissue sampling for mobile spine chordomas: literature review and report of two cases

Zuccato

Witiw

Keith

et al. 2018

Spinal Cord Ser Cases

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Mobile spine chordomas are rare and en bloc resection is recommended, contrary to the usual approach to more common spine tumors. Since en bloc resection of spine chordomas improves disease free survival, it has been recommended that tissue diagnosis be obtained preoperatively when chordoma is considered in the differential diagnosis, in order to guide surgical planning. We present two cases where a preoperative biopsy was considered but not obtained after neuroradiology consultation and imaging review, which may have been managed differently if the diagnosis of spine chordomas were known pre-operatively.

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“…Chordomas are principally midline tumors. In the neuraxis, chordomas are most commonly located in the sacrococcygeal region (50-55%), followed by the cranio-occipital region (25-30%) and then in the mobile spine vertebral bodies (10-15%) [1,[3][4][5][6]. For extra-axial paraspinal lesions, the common pathology are metastatic tumor, neurogenic tumor (schwannoma or neurofibroma) and lymphoma [2].…”

Section: Introductionmentioning

confidence: 99%

Cervical paraspinal chordoma with left vertebral artery encasement

Yip¹,

Lai²,

Tseng³

et al. 2015

IJCRI

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International Journal of Case Reports and Images (IJCRI) is an international, peer reviewed, monthly, open access, online journal, publishing high-quality, articles in all areas of basic medical sciences and clinical specialties.Aim of IJCRI is to encourage the publication of new information by providing a platform for reporting of unique, unusual and rare cases which enhance understanding of disease process, its diagnosis, management and clinico-pathologic correlations. Chordomas are slow-growing, low-grade malignant but locally invasive tumors which originate from embryonic remnants of the primitive notochord. Chordomas are principally midline tumors. In the neuraxis, chordomas are most commonly located in the sacrococcygeal region (50-55%), followed by the cranio-occipital region (25-30%). Case Report: A 71-year-old male has a left paraspinal tumor extending from C2 to C6 with bone erosion and left vertebral artery encasement. The tentative diagnosis before surgery was lymphoma or metastatic tumor. He underwent posterior cervical decompression with surgical debulking of the tumor to release the cord compression and posterior lamina screw fixation from C2 to C7 with allograft fusion and pathology confirmed the tumor to be chordoma. Conclusion: Due to the rare occurrence of chordomas extra-axially, these lesions have not earned a great deal of consideration in the clinical and radiographic differential diagnoses of extra-axial paraspinal lesions. An accurate preoperative diagnosis of chordoma is crucial, as survival is optimal when radical en bloc resection is performed at primary surgery.

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Lumbar chordoma mimicking a neurogenic tumour

Cited by 7 publications

References 15 publications

A giant lumbar chordoma

A giant lumbar chordoma

The importance of preoperative tissue sampling for mobile spine chordomas: literature review and report of two cases

Cervical paraspinal chordoma with left vertebral artery encasement

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