Lumbar Ganglioneuroma from the Paravertebral Body Presenting in Continuity Between Intradural and Extradural Spaces

Takebayashi, Kento; Kohara, Kotaro; Miura, Isamu; Yuzurihara, Mitsutoshi; Kubota, Motoo; Kawamata, Takakazu

doi:10.1016/j.wneu.2019.05.065

Cited by 7 publications

(2 citation statements)

References 11 publications

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“…This tumor frequently occurs in the posterior mediastinum and abdomen [ 2 ]. The incidence of this condition is not well documented, but it is estimated to be about 0.1% to 0.5% of central nervous system tumors [ 3 ]. GNs are predominantly found in women with an average age of diagnosis at seven years old [ 4 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

Paravertebral Ganglioneuroma in Pediatric Age: A Case Report

Lasca,

Laia,

Pires Santos

et al. 2024

Cureus

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Ganglioneuromas (GNs) are rare benign tumors common in the pediatric population. Although mostly asymptomatic, some can cause symptoms, particularly neurological ones. Here, we report a case of a two-year-old male child, who presented changes in gait, an alarming sign, during a child health surveillance appointment. On physical examination, the child presented a “duck” gait pattern, axial and appendicular hypotonia, proximal weakness of the pelvic girdle, and a positive Gowers sign. The child was referred to a pediatric neurology appointment where he underwent neuraxial magnetic resonance imaging, identifying a large and expansive formation in the dorsolumbar transition suggestive of neuroblastoma, considering the age group. However, a computed tomography-guided biopsy revealed it to be a paravertebral GN. Tumor resection was performed, leaving some paravertebral tumor residue. After one year of motor rehabilitation, the child had a normal neurological examination. The child is currently five years old and is undergoing annual clinical and imaging surveillance. This case allows us to reflect on the importance of encouraging children and young people to attend recommended surveillance appointments and reminds us that the rarest situations can occur.

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Section: Introductionmentioning

confidence: 99%

Paravertebral Ganglioneuroma in Pediatric Age: A Case Report

Lasca,

Laia,

Pires Santos

et al. 2024

Cureus

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“…Studies have shown that (2) the morbidity rate of primary gallbladder carcinoma is the highest among various biliary system-related malignant tumors and the top three digestive system malignant tumors. The early clinical manifestations of gallbladder carcinoma are similar to those of simple gallstones or gallbladder inflammation, so it is often ignored, delaying the diagnosis and treatment, and leading to poor prognosis (3). The prognosis and quality of life of gallbladder carcinoma patients are related to the disease stage at the time of diagnosis and whether radical surgery can be performed (4).…”

Section: Introductionmentioning

confidence: 99%

Effects of Thoracic Paravertebral Block on Inflammatory Response, Stress Response, Hemodynamics and Anesthesia Resuscitation in Gallbladder Carcinoma

Liu¹,

Liu²,

et al. 2022

Cell Mol Biol (Noisy-le-grand)

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The study aimed to explore the effects of the ultrasound-guided thoracic paravertebral block (TPVB) on the inflammatory response, stress response, hemodynamics and anesthesia resuscitation in gallbladder carcinoma. Eighty gallbladder carcinoma patients undergoing open cholecystectomy in Heilongjiang Provincial Hospital from February 2016 to April 2019 were selected and divided into observation group (n=40) and control group (n=40) using a random number table. All patients underwent open cholecystectomy under general anesthesia and tracheal intubation. Patient-controlled intravenous analgesia was adopted after the operation in the control group, while right TPVB was performed before general anesthesia in the observation group. The changes in inflammatory factors and oxidative stress factors were compared between the two groups, the anesthesia resuscitation indexes, and the changes in the bispectral index (BIS) and Ramsay score during anesthesia resuscitation were recorded, and the changes in the hemodynamic indexes in perianesthesia and anesthesia resuscitation-related complications were analyzed. At 15 min after anesthesia, the observation group had lower levels of inflammatory factors high-sensitivity C-reactive protein (hs-CRP) and interleukin-6 (IL-6) (p<0.05), malondialdehyde (MDA) (p<0.05) and a higher level of superoxide dismutase (SOD) (p<0.05) than the control group. The anesthesia resuscitation time was shorter in the observation group than that in the control group (p<0.05). At 10 min, 20 min and 30 min after anesthesia, both BIS and Ramsay scores were significantly higher in the observation group than those in the control group (p<0.05). Moreover, the proportion of circulatory function-related complications and anesthesia resuscitation-related complications were lower in the observation group than that in the control group (p<0.05). The NRS score in the observation group was lower than that in the control group after anesthesia (p<0.05). TPVB in perianesthesia for gallbladder carcinoma patients can effectively lower the body's inflammatory and stress responses, promote anesthesia resuscitation, reduce complications in perianesthesia, and relieve postoperative pain.

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