Lumbar Ganglioneuroma Presenting With Scoliosis

Gaddipati, Ravi; Ma, Joanna; Dayawansa, Samantha; Yuan, Shan; Huang, Jason H.; Garrett, David; Qaiser, Rabia

doi:10.7759/cureus.16794

Cited by 2 publications

(1 citation statement)

References 18 publications

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“…Bone scintigraphy typically shows focal uptake. 45 Other cases of tumor-related scoliosis have been reported, including osteoblastoma (an osteoid osteoma of larger size with nidus > 2 cm), 46 ganglioneuroma, 47 or spinal cord tumors, such as pilocytic astrocytoma. 48…”

Section: Lacroix Et Al 538mentioning

confidence: 99%

Scoliosis

Lacroix,

Khalifé,

Ferrero

et al. 2023

Semin Musculoskelet Radiol

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Scoliosis is a three-dimensional spinal deformity that can occur at any age. It may be idiopathic or secondary in children, idiopathic and degenerative in adults. Management of patients with scoliosis is multidisciplinary, involving rheumatologists, radiologists, orthopaedic surgeons, and prosthetists. Imaging plays a central role in diagnosis, including the search for secondary causes, follow-up, and preoperative work-up if surgery is required. Evaluating scoliosis involves obtaining frontal and lateral full-spine radiographs in the standing position, with analysis of coronal and sagittal alignment. For adolescent idiopathic scoliosis, imaging follow-up is often required, accomplished using low-dose stereoradiography such as EOS imaging. For adult degenerative scoliosis, the crucial characteristic is rotatory subluxation, also well detected on radiographs. Magnetic resonance imaging is usually more informative than computed tomography for visualizing associated canal and foraminal stenoses. Radiologists must also have a thorough understanding of postoperative features and complications of scoliosis surgery because aspects can be misleading.

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Section: Lacroix Et Al 538mentioning

confidence: 99%

Scoliosis

Lacroix,

Khalifé,

Ferrero

et al. 2023

Semin Musculoskelet Radiol

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Giant Ganglioneuroma of the Lumbar Spine: A Rare Cause of Radiculopathy

Altalhi,

Alayyaf,

Bin-Mahfooz

et al. 2024

Case Reports in Surgery

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Background. Ganglioneuroma (GN) is a rare, benign tumor that originates from neural crest cells and can potentially affect any anatomical site within the sympathetic nervous system. Typically, GNs are more frequently reported in children and young adults, with a slightly higher prevalence in females. We are reporting a rare case of a giant lumbar spine ganglioneuroma by outlining the clinical presentation, radiological finding, management, and outcome. Case Description. A 37-year-old female presented with low back pain radiating to the right lower limb for few years. Neurological examination revealed bilateral lower limb hyperreflexia (+3). Lumbar spine CT and MRI revealed a right paravertebral soft tissue lesion with heterogeneous signal intensity and enhancement at L1 to L3. The patient underwent complete resection of the lesion via a retroperitoneal approach. The surgery was uneventful. The histopathological sections were suggestive of mature ganglioneuroma. She was discharged in stable condition with follow-up at neurosurgery clinic. Conclusion. Giant ganglioneuromas are rare, benign tumors of sympathetic neurons. Complete surgical resection is the most effective therapeutic option for ganglioneuroma to avoid recurrence. Given the benign nature of ganglioneuroma, chemotherapy and radiotherapy tend to have a limited role following surgical resection.

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Lumbar Ganglioneuroma Presenting With Scoliosis

Cited by 2 publications

References 18 publications

Scoliosis

Scoliosis

Giant Ganglioneuroma of the Lumbar Spine: A Rare Cause of Radiculopathy

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