“…Accordingly, the detection of high ICP through an alternative of clinical and tomographic methods would be useful in monitoring of patients in order to indicate CSF drainage by spinal tap. While failure to address raised intracranial pressure could result in more residual neurological damage and death 1 , the unneeded repetition of spinal taps increases the risk of adverse events, including hemorrhage, bacterial infection, CSF hypotension, radicular involvement, epidermoid tumor, and brain herniation 28 . Therefore, to avoid unneeded lumbar punctures is desirable through the development of a reliable, non-invasive method to measure ICP that is easy to perform at the bedside and can identify the patients who must be subjected to spinal tap.…”