Lumbar Sympathicolysis in Patients with Severe Peripheral Artery Disease: Hemodynamics of the Lower Limbs Determined by Near-Infrared Spectroscopy, Color Coded Duplex Sonography, and Temperature Measurement

Bombor, I; Wissgott, Christian; Andresen, Reimer

doi:10.4137/cmc.s15233

Cited by 3 publications

(2 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, O 2 − uncouples endothelial nitric oxide synthase. Accordingly, nitric oxide production was found to be negatively correlated with plasma glucose and hemoglobin A1c levels in diabetic patients [ 23 ], and the peak systolic velocity of the dorsalis pedis artery was less increased after bilateral lumbar sympathicolysis in diabetic patients than in patients without diabetes mellitus [ 24 ]. Ischemic heart disease also induces oxidative stress where O 2 − reduces nitric oxide concentration and endothelial nitric oxide synthase activity (uncoupling) [ 22 ].…”

Section: Discussionmentioning

confidence: 99%

The Effects of Vasodilation Induced by Brachial Plexus Block on the Development of Postoperative Thrombosis of the Arteriovenous Access in Patients with End-Stage Renal Disease: A Retrospective Study

Kim

Park

Cho

et al. 2022

IJERPH

View full text Add to dashboard Cite

Although brachial plexus block (BPB)-induced vasodilation reduces the incidence of arteriovenous access (AC) thrombosis, BPB cannot completely prevent its development. Therefore, we retrospectively investigated the factors affecting BPB-induced vasodilation and their effects on AC thrombosis development. Ninety-five patients undergoing AC surgery under BPB were analyzed. Vessel diameters were measured before and 20 min after BPB. The surgery abandoned before the BPB placement was performed when the BPB-induced increases in vessel diameters met its indications. Complete occlusive access thrombosis (COAT) was defined as loss of pulse, thrill, or bruit. Fourteen patients (14.7%) developed COAT. The outflow vein was more dilated by BPB than the inflow artery (0.6 versus 0.1 mm in median, p < 0.001). The original surgery plan was changed for seven patients (7.4%). Diabetes mellitus (DM) and ischemic heart disease (IHD) decreased the extent of increases in the inflow artery by −0.183 mm (95% confidence interval [CI] [−0.301, −0.065], p = 0.003) and outflow vein diameters by −0.402 mm (95% CI [−0.781, −0.024], p = 0.038), respectively. However, DM, IHD, and changes in the vessel diameters had insignificant effects on the development of COAT. In conclusion, although DM and IHD attenuate the vasodilating effects of BPB, they do not contribute to the development of COAT.

show abstract

Section: Discussionmentioning

confidence: 99%

The Effects of Vasodilation Induced by Brachial Plexus Block on the Development of Postoperative Thrombosis of the Arteriovenous Access in Patients with End-Stage Renal Disease: A Retrospective Study

Kim

Park

Cho

et al. 2022

IJERPH

View full text Add to dashboard Cite

show abstract

“…The effects of heat exposure on EPR in PAD have not been well understood. Due to limb ischemia, the lower limb temperature is lower and revascularization therapy raised the limb temperature [201]. In addition, a decrease in the Tm induces a decelerated rate of ATP turnover [202], which likely leads to an elevation of ATP concentration in the extracellular space.…”

Section: Heat Treatment (Figuresmentioning

confidence: 99%

Sympathetic Nerve Activity and Blood Pressure Response to Exercise in Peripheral Artery Disease: From Molecular Mechanisms, Human Studies, to Intervention Strategy Development

Qin

Cui

2022

IJMS

View full text Add to dashboard Cite

Sympathetic nerve activity (SNA) regulates the contraction of vascular smooth muscle and leads to a change in arterial blood pressure (BP). It was observed that SNA, vascular contractility, and BP are heightened in patients with peripheral artery disease (PAD) during exercise. The exercise pressor reflex (EPR), a neural mechanism responsible for BP response to activation of muscle afferent nerve, is a determinant of the exaggerated exercise-induced BP rise in PAD. Based on recent results obtained from a series of studies in PAD patients and a rat model of PAD, this review will shed light on SNA-driven BP response and the underlying mechanisms by which receptors and molecular mediators in muscle afferent nerves mediate the abnormalities in autonomic activities of PAD. Intervention strategies, particularly non-pharmacological strategies, improving the deleterious exercise-induced SNA and BP in PAD, and enhancing tolerance and performance during exercise will also be discussed.

show abstract

Effectiveness of Lumbar Sympathetic Block in Patients of Chronic Leg Pain Presented to Pain Clinic at a Tertiary Government Hospital Over Past Two-Years: A Retrospective and Observational Study.

Kulkarni

Lokapur

2021

PIJR

View full text Add to dashboard Cite

Background:Lumbar sympathetic block is used in inoperable peripheral vascular disease. The block acts as a vasodilator by decreasing sympathetic tone and improves tissue oxygenation and helps in ulcer healing. No guidelines exist till date for its use in patients with chronic leg pain and ulcers. The management of patients with unreconstructable distal disease with rest pain has always been difficult. Lumbar sympathetic block helps to abolish this rest pain. Aims and Objectives: 1. To study the effectiveness of lumbar sympathetic block 2. To study the ideal level for needle insertion for 100% success rate. 3. To follow up the patients for 1 week, 4 weeks and 12 weeks for relief of symptoms. 4. To study the safety of the block and note the complications. Materials and Methods: After approval of ethical committee, this retrospective study was conducted from Pain Clinic Records over the past two years. Total number of patients studied were 30 over past 2 years. Data Collection: Demographic Data and VAS score was recorded Preblock walking distance was recorded. CT guided lumbar sympathetic block was given. Results and Conclusion: Lumbar sympathetic block was very useful, safe and effective method to decrease the rest pain in patients presented to pain OPD of our hospital. Follow up for 3 months showed healing of ulcers in some of these patients.

show abstract

Lumbar Sympathicolysis in Patients with Severe Peripheral Artery Disease: Hemodynamics of the Lower Limbs Determined by Near-Infrared Spectroscopy, Color Coded Duplex Sonography, and Temperature Measurement

Cited by 3 publications

References 42 publications

The Effects of Vasodilation Induced by Brachial Plexus Block on the Development of Postoperative Thrombosis of the Arteriovenous Access in Patients with End-Stage Renal Disease: A Retrospective Study

The Effects of Vasodilation Induced by Brachial Plexus Block on the Development of Postoperative Thrombosis of the Arteriovenous Access in Patients with End-Stage Renal Disease: A Retrospective Study

Sympathetic Nerve Activity and Blood Pressure Response to Exercise in Peripheral Artery Disease: From Molecular Mechanisms, Human Studies, to Intervention Strategy Development

Effectiveness of Lumbar Sympathetic Block in Patients of Chronic Leg Pain Presented to Pain Clinic at a Tertiary Government Hospital Over Past Two-Years: A Retrospective and Observational Study.

Contact Info

Product

Resources

About