Rock climbing is an increasingly popular indoor sport with a sizable risk of overuse injuries. Yet, many medical practitioners have little familiarity with evaluating and treating climbing injuries because of the terminology, biomechanical demands, mechanisms of injury, and return to sport counseling needed, unique to the sport. This review seeks to educate practitioners on these aspects. Upper extremity injuries occur more frequently than lower extremity injuries, with finger injuries being most prevalent. Pulley injuries, consisting of rupture of the A2 or A4 annular pulleys are the most common type of injury. Other finger injuries include tenosynovitis of the flexor tendons, as well as lumbrical muscle tears. Elbow injuries occur frequently, with medial epicondylopathy being most common. Brachialis injuries are seldom seen outside of climbing. Lower-extremity injuries are typically more acute in nature, including ankle injuries from falls and knee injuries from strenuous climbing moves.Rock climbing is an increasingly popular sport, especially after its inclusion in the 2020 Olympics. In 2021, 53 new climbing gyms opened in the United States despite the COVID-19 pandemic, totaling 591, around four times the number of gyms that existed in 2000 (1). Now, there are almost twice as many indoor climbers as those who climb outdoors (2). Although generally considered safe, a literature review showed that injuries are still common, with an incidence of between 1.52 and 4.24 per 1000 hours of participation (3). Even with an increasing amount of research on this subject, there are still few publications reviewing climbing injuries with the focus of informing medical practitioners who may encounter them.