Lung Cancer Therapy Using Naturally Occurring Products and Nanotechnology

IMAM, SYED SAIF; IMAM, SYEDA TUBA; Agarwal, Smriti; KUMAR, RISHABH; AMMAR, MD YUSUF; ATHAR, MD WASIF; AKHTAR, ARBAZ

doi:10.22159/ijms.2022.v10i4.44993

Cited by 7 publications

(5 citation statements)

References 41 publications

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“…The observation of biochemical effects that occur before physiologic impacts, such as insulin's control of glucose. a reduction in CRP (c-reactive protein) levels preceded by an anti-inflammatory action [43]. c. Measurements of plasma drug concentration and their relationship to biological therapeutic effects.…”

Section: Methods Used For Monitoring Of Therapeutic Drugsmentioning

confidence: 99%

A Descriptive Analysis of Therapeutic Drug Monitoring In India

Khan,

Uz Zaman

2024

Asian J Pharm Res Dev

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Therapeutic drug monitoring (TDM) has evolved into therapeutic drug management throughout the past three to four decades, becoming a crucial facet of precision medicine. Even though India has one of the fastest-growing economies in the world, TDM is not widely used there. At the moment, it is restricted to a small number of teaching hospitals and academic medical institutes. Other therapeutic domains, such anticancer, antifungal, antibacterial, and antitubercular medications, have shown considerable promise to enhance patient outcomes in Indian settings, aside from immunosuppressive pharmaceuticals. The population of this subcontinent is unique in terms of the importance of TDM due to factors like the higher prevalence of nutritional deficiencies, tropical diseases, the widespread adoption of alternative medicines, unlike pharmacogenomics, and the scarcity of population-specific data on the therapeutic ranges of multiple drugs.TDM has not gotten the interest it merits in India, despite its vast applicability and influence on clinical science. This study aims to present a SWOT (strength, weakness, opportunity, and threats) analysis of TDM in India so that suitable measures for promoting TDM growth can be envisaged. Forming a collaborative group with all the stakeholders—including TDM experts, physicians, and the government—and coming up with a National Action Plan to support TDM are urgent needs. To determine the country's TDM focus areas, nodal TDM facilities should be formed, and pilot programmes should be launched. Capacity development and awareness rising are also important steps towards integrating TDM into traditional clinical practice.

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Section: Methods Used For Monitoring Of Therapeutic Drugsmentioning

confidence: 99%

A Descriptive Analysis of Therapeutic Drug Monitoring In India

Khan,

Uz Zaman

2024

Asian J Pharm Res Dev

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“…More legal security and a more stable environment were made possible by this legislation. It encourages creativity and avoids unfair competition from those that make exaggerated or deceptive promises [44]. The rule does not require anybody to make unfavourable statements about the product if positive assertions are prohibited.…”

Section: Regulation Of Nutraceuticals In Indiamentioning

confidence: 99%

India’s Growing Demand of Nutraceuticals

Ahmad

2024

Asian J Pharm Res Dev

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Nutraceuticals are nutritive ingredients—a cross between food and medicine—that are physiologically active and have the power to preserve optimum health and advantages. These goods are essential to maintaining human health and well-being, especially in light of upcoming treatment advancements. Due to their safety profile, medicinal effects, and nutritional advantages, nutraceuticals have gained popularity. Global demand for nutraceuticals is rising in the areas of disease prevention, health care promotion, and other services. In this overview, several drug-nutritional interactions are additionally outlined using a variety of instances. The concluding portion of the assessment states that there are several patents on nutraceuticals for use in agriculture and in treating a variety of disorders, confirming the exponential rise of the market for nutraceuticals. In addition to being used for nutrition, nutraceuticals have been employed as an adjunct treatment for both the prevention and the treatment of a number of disorders, including the reduction of adverse effects from radiation and chemotherapy for cancer. Nutraceutical formulation development presents a number of obstacles that are often solved by a variety of innovative nano-formulation techniques. Any negative effects of nutraceuticals products may be avoided with the aid of prior knowledge about different medication combinations. Moreover, micronized food items along with additional nutraceutical supplements with enhanced health advantages are produced thanks to nanotechnology. The most recent significant results (clinical research) on nutraceuticals that demonstrate the bioactive compounds in these supplements have a therapeutic effect on a range of ailments have also been included in this review article.

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“…Radiation therapy has the potential to harm healthy tissues, cells, and organs. Despite the fact that chemotherapy has decreased morbidity and death, almost all chemotherapeutic drugs harm healthy cells, particularly those that divide and expand quickly [34][35][36][37]. A significant issue with chemotherapy is drug resistance, which occurs when cancer cells that were originally inhibited by an anticancer treatment start to become resistant to the agent.…”

Section: Conventional Cancer Therapiesmentioning

confidence: 99%

Cancer and New Prospective to Treat Cancer

MEHDI,

CHAUHAN,

DHUTTY

2023

Int J Curr Pharm Sci

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Cancer is a condition when a few of the body's cells grow out of control and spread across other bodily regions. In the millions of cells that make up the human body, cancer may develop practically anywhere. Human cells often divide (via a process known as cell growth and multiplication) to create new cells when the body requires them. New cells replace old ones when they die as a result of ageing or injury. Aside from recent significant advancements in stem cell treatment, targeted therapy, ablation therapy, nanoparticles, natural antioxidants, radionics, chemodynamic therapy, sonodynamic therapy, and ferroptosis-based therapy, traditional treatment modalities like surgery, chemotherapy, and radiotherapy are still in use. Oncology practices today concentrate on creating effective and secure cancer nanomedicines. Targeting both primary and metastatic cancer foci, stem cell treatment has demonstrated remarkable success in regenerating and repairing sick or damaged tissues, and nanoparticles have introduced novel diagnostic and therapeutic possibilities. The development and spread of particular cancer cells can be prevented by targeted treatment, which also protects good cells from harm. Ablation treatment has become a less invasive method for freezing or burning tumours without performing open surgery. Natural antioxidants have shown promise in locating free radicals and counteracting their damaging effects, perhaps treating or preventing cancer. Clinical trials are being conducted on a number of innovative technologies, some of which have already received approval. A summary on current developments and discoveries in cancer therapy was provided in this review.

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Lung Cancer Therapy Using Naturally Occurring Products and Nanotechnology

Cited by 7 publications

References 41 publications

A Descriptive Analysis of Therapeutic Drug Monitoring In India

A Descriptive Analysis of Therapeutic Drug Monitoring In India

India’s Growing Demand of Nutraceuticals

Cancer and New Prospective to Treat Cancer

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