Lung lesions: cytologic diagnosis by fine-needle biopsy.

Stanley, J H; Fish, G D; Andriole, Joseph; Gobien, Rolf P.; Betsill, William L.; Laden, S. Aaron; Schabel, Stephen I.

doi:10.1148/radiology.162.2.3797651

Cited by 164 publications

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“…The sensitivity of FNAC for diagnosing malignancy was found to be 92.59% in our study. This finding is similar to the study done by Singh et al, Stanley et al and Basnet et al 7,13,14 CT guided biopsy was positive in all patients. Small cell carcinoma was seen in 5 (6.17%) patients while nonsmall cell lung carcinoma was seen in 75 (92.59%) patients.…”

Section: Discussionsupporting

confidence: 92%

“…Mean age of presentation was 60.98 yrs which is similar to a study done by Noronha et al 11 We found Non-small cell lung carcinoma, proven on CT guided biopsy, in 75 patients (92.59%) and small cell carcinoma in 6 patients. These findings are similar to the studies done by Shetty et al and Singh et al 12,13 CT guided FNAC yielded positive result in 75 patients. Out of these 75 patients, specific type of lung cancer was confirmed in 58 patients.…”

Section: Discussionsupporting

confidence: 92%

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Comparative study of computed tomography guided fine needle aspiration cytology and trucut biopsy in diagnosis of lung cancer: a report of 81 cases

et al. 2016

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INTRODUCTIONLung cancer is the most commonly diagnosed malignancy across the globe, especially in males. It is the leading cause of cancer related deaths with an average 5 year survival rate of 16.8%.1 CT guided fine needle aspiration cytology (FNAC) and Biopsy are simple methods to diagnose lung cancer in a vast majority of patients, especially in peripherally situated lesions. FNAC was first used by Martin and Ellis as a diagnostic tool.2 FNAC can sub classify the type of bronchogenic carcinoma and the vast majority of lung malignancies can be confidently diagnosed with cyto-morphological characterization in right clinical context. 3 The purpose of our study was to evaluate the diagnostic utility of CT guided FNAC and to compare it with biopsy in diagnosis of lung cancer. METHODSThis is a cross sectional study, done in department of respiratory medicine, Geetanjali Medical College and Hospital , Udaipur, Rajasthan over a period of 12 months from august 2014 to July 2015. Study was approved by Institutional ethical committee. All the patients with suspected mass lesion on chest X-ray and clinical symptoms suggestive of lung cancer were included in the study. Written consent was taken from each patient. Clinical history was taken in detail and routine blood investigations were sent, including BT, CT and INR. ABSTRACTBackground: Lung cancer is the major cause of cancer related deaths all over the world. CT guided FNAC and/or Biopsy of lung mass is an effective modality to diagnose lung cancer, especially in peripherally situated lesions. This study was planned to compare the role of CT guided lung FNAC and Biopsy in diagnosis of Lung cancer. Methods: This is a cross sectional study, done in department of respiratory medicine of a tertiary care teaching hospital of Rajasthan over a period one year. All the patients with suspected mass lesion on chest X-ray and clinical symptoms suggestive of lung cancer were included in the study. CT guided FNAC and biopsy were done in each patient after explaining the risks. Results: CT guided procedures were done in 81 patients of suspected lung cancer. CT guided FNAC yielded positive results in 75 patients while it was negative in 6 patients. CT guided lung biopsy was positive in all patients. Squamous cell carcinoma was most common type encountered malignancy. Conclusions: CT guided lung FNAC and Biopsy is a simple and safe method with high diagnostic accuracy for diagnosis of Lung cancer.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 92%

Comparative study of computed tomography guided fine needle aspiration cytology and trucut biopsy in diagnosis of lung cancer: a report of 81 cases

et al. 2016

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“…omputed tomography (CT)-guided transthoracic fine needle aspiration (TTFNA) biopsy is currently considered a reliable diagnostic technique to assess malignancy of pulmonary nodules and masses (1)(2)(3)(4). CT-guided TTFNA is an invasive technique with low incidence of severe complications and contraindications (1).…”

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confidence: 99%

“…Pneumothorax is the most common complication occurring in the range of 8%-64% (with a risk of tension pneumothorax in about 7% of cases) (1)(2)(3)(4)(5)(6)(7). The risk of pneumothorax increases in the presence of obstructive lung disease and small target lesion.…”

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confidence: 99%

CT-guided biopsy of pulmonary nodules: is pulmonary hemorrhage a complication or an advantage?

Filippo

Saba²,

Silva³

et al. 2014

Diagn Interv Radiol

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ORIGINAL ARTICLE PURPOSEWe aimed to assess the correlation between pulmonary hemorrhage and pneumothorax in computed tomography (CT)-guided transthoracic fine needle aspiration (TTFNA), particularly its possible value as protection against the development of pneumotorax. MATERIALS AND METHODSWe reviewed the CT images of 538 patients (364 males and 174 females, mean age 70 years, range 36-90 years) who underwent CT-guided TTFNA of pulmonary nodules between January 2008 and September 2013. The following CT findings were assessed: pulmonary hemorrhage (type 1, along the needle track; type 2, perilesional; low-grade, ≤6 mm; high-grade, >6 mm), pneumothorax, distance between the target nodule and the pleural surface, and emphysema. RESULTSPneumothorax occurred in 154 cases (28.6%) and pulmonary hemorrhage occurred in 144 cases (26.8%). The incidence of pneumothorax was lower in patients showing type 1 and high-grade pulmonary hemorrhage pattern. The incidence of pneumothorax in biopsies ≥30 mm from pleural surface was 26% (12/46) in cases showing this pattern, while it was 71.4% (30/42) when this pattern was not seen. Similarly, the incidence of pneumothorax in biopsies <30 mm from the pleural surface was 0% (0/28) in cases showing this hemorrhage pattern, while it was 19% (76/394) when this pattern was not seen. CONCLUSION Pulmonary hemorrhage during TTFNA is a frequent event that protects against pneumothorax. A bleeding greater than 6 mm along the needle track is associated with lower incidence of pneumothorax, especially in biopsies deeper than 3 cm.

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“…This ensures proper needle placement and helps to avoid the necrotic areas. Carefully performed transthoracic needle or Tru-cut biopsy can result in an extremely high accuracy rate (90% -98%) of diagnosis of cancer [7][8][9], They are often helpful in indicating the histologic typing of the lesions (77%-83%) [3]. In our series, the diagnosis of malignancy and cell typing were possible in almost all cases.…”

Section: Discussionmentioning

confidence: 71%

Ct-Guided Fnac and Biopsy : Our Experience

Ram¹,

Joshi²,

Pant³

et al. 1995

Medical Journal Armed Forces India

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Twenty five patients with mass lesions in the chest, abdomen, pelvis, and paraspinal region underwent contrast enhanced computed tomographic scan (CT Scan) followed by CT guided FNAC or Tru-cut biopsy. CT was found to be extremely valuable in ensuring needle placement within the lesion. It also helped in avoiding the necrotic areas and obtaining tissue from an area most likely to yield an adequate sample. A post-procedure scan helped in ruling out post-procedure complications.M J A F I 1 0 9 5 ; 51 : 251-254

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Lung lesions: cytologic diagnosis by fine-needle biopsy.

Cited by 164 publications

References 0 publications

Comparative study of computed tomography guided fine needle aspiration cytology and trucut biopsy in diagnosis of lung cancer: a report of 81 cases

Comparative study of computed tomography guided fine needle aspiration cytology and trucut biopsy in diagnosis of lung cancer: a report of 81 cases

CT-guided biopsy of pulmonary nodules: is pulmonary hemorrhage a complication or an advantage?

Ct-Guided Fnac and Biopsy : Our Experience

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