Lung Transplantation for Idiopathic Pulmonary Fibrosis: A Narrative Review

Mehfooz, Nazia; Siraj, Farhana; Koul, Parvaiz A

doi:10.4103/ijrc.ijrc_18_20

Cited by 1 publication

(2 citation statements)

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“…Complications reported in acute care were consistent with other reports of patients with COVID‐19, including respiratory failure, hematologic complications, rheumatologic complications, weakness, and renal failure 33,35–37 . Postoperative complications were also consistent with reported complications of patients who underwent BOLT for reasons other than COVID‐19, including infection, pneumothorax, bleeding, renal failure, and weakness 8,34,38,39 . Acute hospital readmissions from IPR are seen among non‐COVID‐19 lung transplant patients with variable readmission rates that can range from 19–40% 8,12 .…”

Section: Discussionsupporting

confidence: 79%

“…33,[35][36][37] Postoperative complications were also consistent with reported complications of patients who underwent BOLT for reasons other than COVID-19, including infection, pneumothorax, bleeding, renal failure, and weakness. 8,34,38,39 Acute hospital readmissions from IPR are seen among non-COVID-19 lung transplant patients with variable readmission rates that can range from 19-40%. 8,12 It is not surprising that this patient population had a greater percentage of readmission rates to acute care (47%) given the greater medical complexity of these patients compared to those not infected with COVID-19.…”

Section: Medical Complicationsmentioning

confidence: 99%

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Functional improvements of patients admitted to an inpatient rehabilitation facility after bilateral lung transplant due to severe COVID‐19 pulmonary disease

Goodman

Jensen

Walaszek

et al. 2023

PM&R

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BackgroundCoronavirus disease (COVID‐19) has introduced a new subset of patients with acute end‐stage lung damage for which lung transplantation has been successfully performed.ObjectiveTo describe the inpatient rehabilitation course of patients who underwent bilateral lung transplant due to severe COVID‐19 pulmonary disease.DesignRetrospective chart review.SettingFree‐standing, academic, urban inpatient rehabilitation hospital.ParticipantsSeventeen patients aged 28–67 years old (mean 53.9 ± 10.7) who developed COVID‐19 respiratory failure and underwent bilateral lung transplant.InterventionsPatients participated in a comprehensive inpatient rehabilitation program including physical, occupational, and speech therapy tailored to the unique functional needs of each individual.Main Outcome MeasuresPrimary outcome measures of functional improvements, include mobility and self‐care scores on section GG of the Functional Abilities and Goals of the Improving Post‐Acute Care Transformation Act, as defined as quality measures by the Centers for Medicare and Medicaid Services. Other functional measures included 6 minute walk test, Berg balance scale, Mann Assessment of Swallowing Ability (MASA), and Cognition and Memory Functional Independence Measure (FIM) scores. Wilcoxon signed rank sum test was used to evaluate statistical significance of change between admission and discharge scores.ResultsFourteen patients completed inpatient rehabilitation. Self‐care (GG0130) mean score improved from 20.9 to 36.1. Mobility (GG0170) mean score improved from 30.7 to 70.7. Mean 6‐minute walk distance improved from 174.1 to 467.6 feet. Mean Berg balance scores improved from 18.6/56 to 36.3/56. MASA scores improved from 171.3 to 182.3. All functional measures demonstrated statistically significant improvements with p value ≤ .008, except for cognition and memory FIM scores, which did not show a statistically significant difference. A majority (76%) of patients discharged home.ConclusionThis new and unique patient population can successfully participate in a comprehensive inpatient rehabilitation program and achieve functional improvements despite medical complications.

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Section: Discussionsupporting

confidence: 79%