Lung transplantation in China: a firm foundation for a solid future

Aryal, Shambhu

doi:10.21037/atm.2020.02.165

Cited by 4 publications

(3 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The continued growth and success of lung transplantation in China is partly due to a well-validated multidisciplinary approach to patient care that extends from the pre-transplantation period through the post-transplantation course. Additionally, the growth and development of lung transplantation in China have been helped by a legal system construct that guarantees organ procurement and utilization (10). Sharing and comparing China's experiences with the rest of the world may provide important lessons for the future of lung transplantation.…”

Section: Introductionmentioning

confidence: 99%

Epidemiology and Prognosis of Invasive Fungal Disease in Chinese Lung Transplant Recipients

Chen

Lian

et al. 2021

Front. Med.

View full text Add to dashboard Cite

This study explored the epidemiology, risk factors, and prognosis of invasive fungal disease (IFD) in Chinese lung transplant recipients (LTRs). This retrospective cohort study included patients who received lung transplants at four hospitals in South China between January 2015 and June 2019. The participants were divided into IFD and non-IFD (NIFD) groups. The final analysis included 226 LTRs (83.2% males) aged 55.0 ± 14.2 years old. Eighty-two LTRs (36.3%) developed IFD (proven or probable diagnosis). The most common pathogens were Aspergillus (57.3%), Candida (19.5%), and Pneumocystis jiroveci (13.4%). Multivariate logistic regression revealed that anastomotic disease [odds ratio (OR): 11.86; 95% confidence interval (95%CI): 4.76–29.54; P < 0.001], cytomegalovirus (CMV) pneumonia (OR: 3.85; 95%CI: 1.88–7.91; P = 0.018), and pre-transplantation IFD (OR: 7.65; 95%CI: 2.55–22.96; P < 0.001) were associated with higher odds of IFD, while double-lung transplantation (OR: 0.40; 95%CI: 0.19–0.79; P = 0.009) was associated with lower odds of IFD. Logistic regression analysis showed that anastomotic disease was associated with higher odds of death (OR: 5.01; 95%CI: 1.24–20.20; P = 0.02) and that PJP prophylaxis was associated with lower odds of death (OR: 0.01; 95%CI: 0.001–0.11; P < 0.001). Invasive fungal disease is prevalent among LTRs in southern China, with Aspergillus the most common pathogen. Prophylaxis should be optimized based on likely pathogens.

show abstract

Section: Introductionmentioning

confidence: 99%

Epidemiology and Prognosis of Invasive Fungal Disease in Chinese Lung Transplant Recipients

Chen

Lian

et al. 2021

Front. Med.

View full text Add to dashboard Cite

show abstract

“…As per a review article by Aryal and Nathan [ 22 ], 1- and 3-year survivals post-lung transplant patients are reported at 70.11% and 61.16%, respectively (China Lung Transplant Registry). In the ISHLT Registry, for the era of 2010–June 2017, the 1- and 3-year survivals were 84.8% and 70.3%, respectively.…”

Section: Our Indian Experiencementioning

confidence: 99%