Lung Tumor Skin Metastasis: Case Report of a Solitary Cutaneous Ulcerated Lesion as Initial Manifestation of Lung Carcinoma

Falbo, Francesco; Krizzuk, Dimitri; Urciuoli, Paolo; Biancucci, Andrea; Galiffa, Giampaolo; Donello, Claudia; Esposito, Anna; Mongardini, Federico Maria; Sammartino, Francesco

doi:10.1159/000527077

Cited by 2 publications

(2 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…But the response is minimal because of the poor blood supply to the skin. Radiation therapy is usually indicated for pain and bleeding [ 6 , 10 ].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Cutaneous metastasis as a first presentation of lung carcinoma: a case series

Sakhri¹,

Zemni²,

Ayadi³

et al. 2023

J Med Case Reports

View full text Add to dashboard Cite

Introduction Cutaneous metastases (CM) revealing lung carcinoma are extremely rare, accounting for 0.8%. The diagnosis is guided by histology and immunohistochemistry. Treatment is palliative. The prognosis is poor. Case presentation This is a retrospective study of the available clinical and histological records of four North African patients with CM revealing lung cancer treated at our institute between 2004 and 2010. Three men and one woman were registered. The mean age was 54.5 years (38–74 years). Two patients had primary adenocarcinoma, one patient had small cell carcinoma and one had squamous cell carcinoma. Treatment was based on chemotherapy in two cases and antalgic radiotherapy in two cases, one patient underwent surgical resection as the lesion was infected. The overall survival after diagnosis was between one and four months. Conclusions A skin nodule can be the first symptom revealing lung cancer. A rare clinical presentation that should not be taken for a benign nodule, the biopsy and histological study with immunohistochemistry confirm the diagnosis.

show abstract

“…But the response is minimal because of the poor blood supply to the skin. Radiation therapy is usually indicated for pain and bleeding [ 6 , 10 ].…”

Section: Discussionmentioning

confidence: 99%

“…The prognosis remains poor and the survival rate after diagnosis varies between three and five months. Prognostic factors are small cell carcinoma, undifferentiated tumor, multiple metastatic lesions, and other distant metastases [ 2 , 10 , 11 ].…”

Section: Discussionmentioning

confidence: 99%

Cutaneous metastasis as a first presentation of lung carcinoma: a case series

Sakhri¹,

Zemni²,

Ayadi³

et al. 2023

J Med Case Reports

View full text Add to dashboard Cite

show abstract

Lung Adenocarcinoma Presenting as Abdominal Skin Metastasis – A Case Report with Extensive Literature Review

Verma,

Kanakapudi,

Bharti

et al. 2024

Preprint

View full text Add to dashboard Cite

Skin metastasis is the spread of malignant cells to the skin from a primary malignancy. It is quite uncommon for skin or cutaneous metastasis of internal malignancies to manifest as an initial presentation. It occurs in about 5.3% of patients with internal malignancies, representing 2% of all skin tumors. Lung Cancer (LC) has the highest incidence and is the most common cause of cancer death worldwide. Metastasis to the skin should be carefully investigated to rule out a metastatic manifestation of an occult primary site tumor. It mostly occurs late in the course of the disease & indicates a poor prognosis. We report a case of a 65-year-old male presenting with multiple abdominal skin nodules as an initial uncommon presentation of unknown primary along with the review of literature for which we performed a Medline search for articles on cutaneous metastases from internal malignancies including LC, using PubMed, and manual search of pertinent references and textbooks.

show abstract

Lung Tumor Skin Metastasis: Case Report of a Solitary Cutaneous Ulcerated Lesion as Initial Manifestation of Lung Carcinoma

Cited by 2 publications

References 14 publications

Cutaneous metastasis as a first presentation of lung carcinoma: a case series

Cutaneous metastasis as a first presentation of lung carcinoma: a case series

Lung Adenocarcinoma Presenting as Abdominal Skin Metastasis – A Case Report with Extensive Literature Review

Contact Info

Product

Resources

About