Lung Ultrasound Can Predict the Clinical Course and Severity of COVID-19 Disease

Ravetti, Cecilia Gómez; Vassallo, Paula Frizera; Barros, Guilherme; Rocha, Guilherme Carvalho; Chamon, Samuel; Borges, Isabela Nascimento; Marinho, Carolina Coimbra; Cabral, Máderson Alvares de Souza; Duani, Helena; Andrade, Marcus V.; Nobre, Vandack

doi:10.1016/j.ultrasmedbio.2021.04.026

Cited by 11 publications

(8 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Baseline diagnosis can cause several of the LUS findings, but the correlation of LUSS with FiO 2 needed, the differences between disease severity and ventilatory support groups, and the decrease with patient improvement show its usefulness as a monitoring tool. As shown by different publications, LUS is a useful tool in clinical examination and can quantify the loss of aeration at the bedside (29,30). Sequential assessments can help the clinician identify improvement or worsening; thus, they can be used to classify the severity of the disease and follow its progress (31).…”

Section: Discussionmentioning

confidence: 99%

Lung Ultrasound Characteristics in Neonates With Positive Real Time Polymerase Chain Reaction for SARS-CoV-2 on a Tertiary Level Referral Hospital in Mexico City

et al. 2022

View full text Add to dashboard Cite

IntroductionAcute respiratory syndrome secondary to SARS-CoV-2 virus infection has been declared a pandemic since December 2019. On neonates, severe presentations are infrequent but possible. Lung ultrasound (LUS) has been shown to be useful in diagnosing lung involvement and following up patients, giving more information, and reducing exposure compared to traditional examination.MethodsLUS was performed after the diagnosis of SARS-CoV-2 infection with respiratory Real Time Polymerase Chain Reaction RT-PCR with portable equipment protected with a silicone sleeve. If hemodynamic or cardiology consultation was necessary, a prepared complete ultrasound machine was used. Ten regions were explored (anterior superior and inferior, lateral, and posterior superior and inferior, right and left), and a semiquantitative score (LUSS) was calculated. Disease severity was determined with a pediatric modified score.ResultsThirty-eight patients with positive RT-PCR were admitted, 32 (81%) of which underwent LUS. Included patients had heterogenous diagnosis and gestational ages as expected on a referral neonatal intensive care unit (NICU) (median, ICR: 36, 30–38). LUS abnormalities found were B-line interstitial pattern 90%, irregular/interrupted/thick pleural line 88%, compact B-lines 65%, small consolidations (≤5 mm) 34%, and extensive consolidations (≥5 mm) 37%. Consolidations showed posterior predominance (70%). LUSS showed a median difference between levels of disease severity and ventilatory support (Kruskal–Wallis, p = 0.001) and decreased with patient improvement (Wilcoxon signed-rank test p = 0.005). There was a positive correlation between LUSS and FiO2 needed (Spearman r = 0.72, p = 0.01). The most common recommendation to the attending team was pronation (41%) and increase in positive end expiratory pressure (34%). Five patients with comorbidities died. A significant rank difference of LUSS and FiO2 needed between survivors and non-survivors was found (Mann–Whitney U-test, p = 0.005).ConclusionLUS patterns found were like the ones described in other series (neonatal and pediatrics). Eighty-eight percent of the studies were performed with handheld affordable equipment. While there is no specific pattern, it varies according to gestational age and baseline diagnosis LUS, which were shown to be useful in assessing lung involvement that correlated with the degree of disease severity and respiratory support.

show abstract

Section: Discussionmentioning

confidence: 99%

Lung Ultrasound Characteristics in Neonates With Positive Real Time Polymerase Chain Reaction for SARS-CoV-2 on a Tertiary Level Referral Hospital in Mexico City

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Several studies have also assessed the dynamic changes in LUS findings during a COVID-19 infection and found that LUS can be used to monitor disease progression during hospitalization [ 1 , 19 , 20 ]. However, whether the LUS findings detected during the initial COVID-19 infection resolve or persist after hospital discharge is less well investigated.…”

Section: Introductionmentioning

confidence: 99%

Lung ultrasound findings following COVID-19 hospitalization: A prospective longitudinal cohort study

Espersen

Platz

Alhakak

et al. 2022

Respiratory Medicine

View full text Add to dashboard Cite

“…The LUS score has shown to be highly sensitive in predicting ICU admission; every 1-point rise in LUS increases the odds of ICU admission by almost 50% ( 98 , 99 ). Patients admitted to the ICUs have higher LUS score on admission than those who did not require hospitalisation or were admitted to non-critical care wards ( 98 - 100 ), and all ICU patients had abnormal LUS findings on admission ( 101 ).…”

Section: Discussionmentioning

confidence: 99%

Point-of-care ultrasound use in COVID-19: a narrative review

Chua,

Boon,

Yeoh

et al. 2024

Ann Transl Med

View full text Add to dashboard Cite

Background and Objective The coronavirus disease 2019 (COVID-19) pandemic that began in early 2020 resulted in significant mortality from respiratory tract infections. Existing imaging modalities such as chest X-ray (CXR) lacks sensitivity in its diagnosis while computed tomography (CT) scan carries risks of radiation and contamination. Point-of-care ultrasound (POCUS) has the advantage of bedside testing with higher diagnostic accuracy. We aim to describe the various applications of POCUS for patients with suspected severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in the emergency department (ED) and intensive care unit (ICU). Methods We performed literature search on the use of POCUS in the diagnosis and management of COVID-19 in MEDLINE, Embase and Scopus databases using the following search terms: “ultrasonography”, “ultrasound”, “COVID-19”, “SARS-CoV-2”, “SARS-CoV-2 variants”, “emergency services”, “emergency department” and “intensive care units”. Search was performed independently by two reviewers with any discrepancy adjudicated by a third member. Key Content and Findings Lung POCUS in patients with COVID-19 shows different ultrasonographic features from pulmonary oedema, bacterial pneumonia, and other viral pneumonia, thus useful in differentiating between these conditions. It is more sensitive than CXR, and more accessible and widely available than CT scan. POCUS can be used to diagnose COVID-19 pneumonia, screen for COVID-19-related pulmonary and extrapulmonary complications, and guide management of ICU patients, such as timing of ventilator weaning based on lung POCUS findings. Conclusions POCUS is a useful and rapid point-of-care modality that can be used to aid in diagnosis, management, and risk stratification of COVID-19 patients in different healthcare settings.

show abstract

Lung Ultrasound Can Predict the Clinical Course and Severity of COVID-19 Disease

Cited by 11 publications

References 24 publications

Lung Ultrasound Characteristics in Neonates With Positive Real Time Polymerase Chain Reaction for SARS-CoV-2 on a Tertiary Level Referral Hospital in Mexico City

Lung Ultrasound Characteristics in Neonates With Positive Real Time Polymerase Chain Reaction for SARS-CoV-2 on a Tertiary Level Referral Hospital in Mexico City

Lung ultrasound findings following COVID-19 hospitalization: A prospective longitudinal cohort study

Point-of-care ultrasound use in COVID-19: a narrative review

Contact Info

Product

Resources

About